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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Enkephalin-leu,ala(2)
Molecular formula	C29H39N5O7
IUPAC name	2-[[2-[[2-[2-[[2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoylamino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoic acid
Molecular weight	569.659
Hydrogen bond acceptor	8
Hydrogen bond donor	7
XlogP	-1.9
Synonyms	(D-Ala2,D-Leu5)enkephalin D-Leucine, N-(N-(N-(N-L-tyrosyl-D-alanyl)glycyl)-L-phenylalanyl)- Leuphasyl UNII-HB4QD9GL6F 2-[2-(2-{2-[2-amino-3-(4-hydroxyphenyl)propanamido]propanamido}acetamido)-3-phenylpropanamido]-4-methylpentanoic acid NSC 374895 [D-Ala2] Leu-Enkephalin AC1L2C3P L024011 PO4D55T1IG EINECS 265-291-0 LS-87867 UNII-PO4D55T1IG 2-[[2-[[2-[2-[[2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoylamino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoic acid HB4QD9GL6F NSC-374895 [D-Ala2]-Leucine enkephalin, >=97% (HPLC) CA-1404 Leucine enkephalin-2-alanine Tyr-D-Ala-Gly-Phe-Leu 2-Alanyl-leucine enkephalin ENKEPHALIN, LEUCINE-2-ALANINE N-(N-(N-(N-L-Tyrosyl-D-alanyl)glycyl)-L-phenylalanyl)-L-leucine [D-Ala2,Leu5]-ENKEPHALIN 5-Leucine-2-alanine enkephalin L-leucine, N-(N-(N-(N-L-Tyrosyl-D-alanyl)glycyl)-L-phenylalanyl)- NSC374895 [ Show all ]
Inchi Key	ZHUJMSMQIPIPTF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C29H39N5O7/c1-17(2)13-24(29(40)41)34-28(39)23(15-19-7-5-4-6-8-19)33-25(36)16-31-26(37)18(3)32-27(38)22(30)14-20-9-11-21(35)12-10-20/h4-12,17-18,22-24,35H,13-16,30H2,1-3H3,(H,31,37)(H,32,38)(H,33,36)(H,34,39)(H,40,41)
PubChem CID	44568
ChEMBL	N/A
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor. This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
428873	Delta-type opioid receptor	P41143	OPRD1	Homo sapiens (Human)	372
428870	Mu-type opioid receptor	P79350	OPRM1	Bos taurus (Bovine)	401
428871	Mu-type opioid receptor	P97266	OPRM1	Cavia porcellus (Guinea pig)	98
428872	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400

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