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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Cleland's reagent
Molecular formula	C4H10O2S2
IUPAC name	1,4-bis(sulfanyl)butane-2,3-diol
Molecular weight	154.242
Hydrogen bond acceptor	4
Hydrogen bond donor	4
XlogP	-0.4
Synonyms	CHEMBL47903 1,4-Dimercaptobutane-2,3-diol D-8220 2,3-Butanediol, 1,4-dimercapto-, (R,R)- (+-)- DL-Theo-1,4-dimercapto-2,3-butanediol 2,3-Butanediol, 1,4-dimercapto-, DL-threo- EINECS 248-531-9 2028-EP2275412A1 LS-45824 2028-EP2292615A1 Sputolysin 2028-EP2305648A1 WR 34678 2028-EP2311829A1 AI3-62064 BRN 1719757 (R,R)-1,4-Dimercaptobutane-2,3-diol (R-(R,R))-1,4-Dimercaptobutane-2,3-diol Clelands reagent 1,4-Dithiothreitol Dithiothreitol 2,3-Butanediol, 1,4-dimercapto-, (R-(R,R))- DTT 2,3-Dihydroxybutane-1,4-dithiol KS-00000YG3 2028-EP2281818A1 MolPort-003-665-010 2028-EP2301928A1 Threitol, 1,4-dithio-, DL- 2028-EP2308880A1 27565-41-9 AN-20224 (+/-)-threo-1,4-Dimercapto-2,3-butanediol CCRIS 3617 CHEBI:25189 1,4-Bissulfanylbutane-2,3-diol D-8100 2,3-Butanediol, 1,4-dimercapto-, (2R,3R)-rel- dl-Dithiothreitol 2,3-BUTANEDIOL, 1,4-DIMERCAPTO-, D-threo- EINECS 231-563-2 2028-EP2270004A1 L-threo-1,4-Dimercapto-2,3-butanediol 2028-EP2289893A1 SC-15337 2028-EP2305633A1 trans-1,4-Dimercaptobutane-2,3-diol 2028-EP2311825A1 AC1L2D93 BRD-A30142024-001-01-1 (R,R)-(1)-1,4-Dimercaptobutane-2,3-diol (R,S)-1,4-Dimercapto-2,3-butanediol Cleland reagent 1,4-Disulfanyl-2,3-butanediol, dl, threo- D01GMJ 2,3-Butanediol, 1,4-dimercapto-, (R,R)-(.+/-.)- DL-threo-1,4-Dimercapto-2,3-butanediol 2,3-BUTANEDIOL, 1,4-DIMERCAPTO-, L-threo- ERYTHRITOL, 1,4-DITHIO- 2028-EP2275414A1 LS-64630 2028-EP2295407A1 STL451520 2028-EP2305825A1 2028-EP2314575A1 AKOS004910031 BRN 2036371 1,4-bis(sulfanyl)butane-2,3-diol CTK5E2800 16096-97-2 Dithiotreitol 2,3-Butanediol, 1,4-dimercapto-, (theta,S)- EINECS 222-468-7 2028-EP2269988A2 L-1,4-Dithiothreitol 2028-EP2289883A1 rac-Dithiothreitol 2028-EP2301930A1 Threitol, 1,4-dithio-, L- 2028-EP2311808A1 3483-12-3 ANW-43982 (.+/-.)-Dithiothreitol CD-473 1,4-dimercapto-2,3-butanediol D-8200 2,3-Butanediol, 1,4-dimercapto-, (R,R)- DL-DTT 2,3-Butanediol, 1,4-dimercapto-, dl, threo- EINECS 240-263-0 2028-EP2270505A1 LS-45823 2028-EP2292593A2 SCHEMBL87345 2028-EP2305640A2 VHJLVAABSRFDPM-UHFFFAOYSA-N 2028-EP2311827A1 AC1Q77NV BRN 1719756 (R,R)-1,4-Dimercapto-2,3-butanediol (R,S)-1,4-Dimercaptobutane-2,3-diol 1,4-disulfanylbutane-2,3-diol D3647 2,3-Butanediol, 1,4-dimercapto-, (R,S)- DTE 2,3-Butanediol,1,4-dimercapto- InChI=1/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H 2028-EP2281815A1 MCULE-7432075835 2028-EP2298736A1 Threitol, 1,4-dithio- 2028-EP2308833A2 2028-EP2316937A1 AN-18114 CCG-208027 CHEBI:18320 1,4-bis-sulfanylbutane-2,3-diol d,l-dithiothreitol 2,3-Butanediol, 1,4-dimercapto- DL-1,4-Dimercapto-2,3-butanediol 2,3-Butanediol, 1,4-dimercapto-, (theta,theta)-(+/-)- EINECS 229-998-8 2028-EP2269993A1 L-Dithiothreitol 2028-EP2289890A1 rel-(2R,3R)-1,4-disulfanylbutane-2,3-diol 2028-EP2301933A1 TR-006842 2028-EP2311814A1 7634-42-6 BCP24764 (R,R)-(+-)-1,4-Dimercapto-2,3-butanediol [ Show all ]
Inchi Key	VHJLVAABSRFDPM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2
PubChem CID	19001
ChEMBL	CHEMBL47903
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
355259	Mu-type opioid receptor	P79350	OPRM1	Bos taurus (Bovine)	401

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