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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL350384
Molecular formula	C20H29NO2
IUPAC name	1-ethyl-10-[(1-hydroxycyclopropyl)methyl]-13,13-dimethyl-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol
Molecular weight	315.457
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	3.9
Synonyms	AKOS030531265 6-Ethyl-1,2,3,4,5,6-hexahydro-3-[(1-hydroxycyclopropyl)methyl]-11,11-dimethyl-2,6-methano-3-benzazocin-8-ol AC1L1AZW LS-89504 BDBM50013388 6-Ethyl-3-(1-hydroxy-cyclopropylmethyl)-11,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol AC1Q77X9 SCHEMBL11246286 6-Ethyl-1,2,3,4,5,6-hexahydro-3-((1-hydroxycyclopropyl)methyl)-11,11-dimethyl-2,6-methano-3-benzazocin-8-ol BREMAZOCINE(-) 71990-00-6 L000925 [ Show all ]
Inchi Key	ZDXGFIXMPOUDFF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H29NO2/c1-4-20-9-10-21(13-19(23)7-8-19)17(18(20,2)3)11-14-5-6-15(22)12-16(14)20/h5-6,12,17,22-23H,4,7-11,13H2,1-3H3
PubChem CID	1223
ChEMBL	CHEMBL350384
IUPHAR	N/A
BindingDB	50013388
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
425992	Delta-type opioid receptor	P41143	OPRD1	Homo sapiens (Human)	372
462828	Delta-type opioid receptor	P79291	OPRD1	Sus scrofa (Pig)	228
425987	Kappa-type opioid receptor	P41145	OPRK1	Homo sapiens (Human)	380
425989	Kappa-type opioid receptor	P41144	OPRK1	Cavia porcellus (Guinea pig)	380
425988	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400
425990	Mu-type opioid receptor	P79350	OPRM1	Bos taurus (Bovine)	401
425991	Mu-type opioid receptor	P97266	OPRM1	Cavia porcellus (Guinea pig)	98
425993	Neuropeptides B/W receptor type 1	P48145	NPBWR1	Homo sapiens (Human)	328

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