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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Mu-type opioid receptor
Species	Bos taurus (Bovine)
Gene	OPRM1
Synonym	M-OR-1 MOR-1
Disease	N/A for non-human GPCRs
Length	401
Amino acid sequence	MDSGAVPTNASNCTDPFTHPSSCSPAPSPSSWVNFSHLEGNLSDPCGPNRTELGGSDRLCPSAGSPSMITAIIIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDLRTPRNAKIINICNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPILIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETTPLP
UniProt	P79350
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3041
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL285250
Molecular formula	C15H21NO
IUPAC name	3-(2-methyl-2-azabicyclo[3.3.1]nonan-5-yl)phenol
Molecular weight	231.339
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	3.2
Synonyms	(?)-3-(2-Methyl-2-azabicyclo[3.3.1]nonan-5-yl)phenol 3-(2-Methyl-2-aza-bicyclo[3.3.1]non-5-yl)-phenol D08UZJ AKOS022657931 2-Methyl-5-(3-hydroxyphenyl)-2-azabicyclo[3.3.1]nonane 3-(2-Methyl-2-azabicyclo[3.3.1]nonan-5-yl)phenol DTXSID80494706 BDBM50000570 27107-68-2 CTK0I5787 Phenol, 3-(2-methyl-2-azabicyclo[3.3.1]non-5-yl)- [ Show all ]
Inchi Key	ZQJGRSYDDMBMPJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C15H21NO/c1-16-9-8-15(7-3-5-13(16)11-15)12-4-2-6-14(17)10-12/h2,4,6,10,13,17H,3,5,7-9,11H2,1H3
PubChem CID	12368881
ChEMBL	CHEMBL285250
IUPHAR	N/A
BindingDB	50000570
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	3.4 nM	PMID1315868	ChEMBL
Ki	13.0 nM	PMID1315868	BindingDB,ChEMBL
Ki	19.0 nM	PMID1315868	BindingDB,ChEMBL
Ki	63.0 nM	PMID1315868	BindingDB,ChEMBL

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