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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Mu-type opioid receptor
Species	Bos taurus (Bovine)
Gene	OPRM1
Synonym	M-OR-1 MOR-1
Disease	N/A for non-human GPCRs
Length	401
Amino acid sequence	MDSGAVPTNASNCTDPFTHPSSCSPAPSPSSWVNFSHLEGNLSDPCGPNRTELGGSDRLCPSAGSPSMITAIIIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDLRTPRNAKIINICNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPILIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETTPLP
UniProt	P79350
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3041
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL287726
Molecular formula	C16H23NO
IUPAC name	3-[(9S)-2,9-dimethyl-2-azabicyclo[3.3.1]nonan-5-yl]phenol
Molecular weight	245.366
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	3.7
Synonyms	SCHEMBL6288108 3-(2,9-Dimethyl-2-aza-bicyclo[3.3.1]non-5-yl)-phenol BDBM50000571
Inchi Key	JBSRPCWYMOJXAM-UWTIGNOOSA-N
Inchi ID	InChI=1S/C16H23NO/c1-12-15-7-4-8-16(12,9-10-17(15)2)13-5-3-6-14(18)11-13/h3,5-6,11-12,15,18H,4,7-10H2,1-2H3/t12-,15?,16?/m1/s1
PubChem CID	44285029
ChEMBL	CHEMBL287726
IUPHAR	N/A
BindingDB	50000571
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	<600.0 nM	PMID1315868	BindingDB,ChEMBL
Ki	18.0 nM	PMID1315868	BindingDB,ChEMBL
Ki	46.0 nM	PMID1315868	BindingDB,ChEMBL
Ki	50.0 nM	PMID1315868	ChEMBL
Ki	140.0 nM	PMID1315868	ChEMBL
Ki	190.0 nM	PMID1315868	ChEMBL

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