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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Hydromorphine
Molecular formula	C17H21NO3
IUPAC name	3-methyl-2,4,4a,5,6,7,7a,13-octahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7,9-diol
Molecular weight	287.359
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	1.8
Synonyms	L000955 NSC117865 CAS_509-60-4 Morphinan-3,6-diol, 4,5-epoxy-17-methyl-, (5.alpha.,6.alpha.)- Paramorphan .alpha.-Dihydromorphine DIHYDROBROMORPHINE Morphine, dihydro- AC1L6SLS Morphinan-3, 4,5-epoxy-17-methyl-, (5.alpha.,6.alpha.)- NSC_273032 (5.alpha.,6.alpha.)-4,5-Epoxy-17-methylmorphinan-3,6-diol Morphinan-3,6.alpha.-diol, 4,5.alpha.-epoxy-17-methyl- SCHEMBL6123637 6.alpha.-Hydromorphol Dihydromorfin IJVCSMSMFSCRME-UHFFFAOYSA-N NSC-117865 BDBM86518 Morphinan-3, 4,5.alpha.-epoxy-17-methyl- Paramorfan CHEMBL608541 FT-0667072 Morphine, 7,8-dihydro- WLN: T B6566 B6/CO 4ABBC R BX HO PN GHT&&TTJ FQ JQ P1 [ Show all ]
Inchi Key	IJVCSMSMFSCRME-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H21NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2,4,10-11,13,16,19-20H,3,5-8H2,1H3
PubChem CID	273032
ChEMBL	CHEMBL608541
IUPHAR	N/A
BindingDB	86518
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
134999	Delta-type opioid receptor	P41143	OPRD1	Homo sapiens (Human)	372
134995	Kappa-type opioid receptor	Q2KIP6	OPRK1	Bos taurus (Bovine)	380
134996	Kappa-type opioid receptor	P41144	OPRK1	Cavia porcellus (Guinea pig)	380
135000	Kappa-type opioid receptor	P41145	OPRK1	Homo sapiens (Human)	380
134993	Mu-type opioid receptor	P79350	OPRM1	Bos taurus (Bovine)	401
134994	Mu-type opioid receptor	P97266	OPRM1	Cavia porcellus (Guinea pig)	98
134997	Mu-type opioid receptor	P33535	Oprm1	Rattus norvegicus (Rat)	398
134998	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400

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