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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Mu-type opioid receptor
Species	Bos taurus (Bovine)
Gene	OPRM1
Synonym	M-OR-1 MOR-1
Disease	N/A for non-human GPCRs
Length	401
Amino acid sequence	MDSGAVPTNASNCTDPFTHPSSCSPAPSPSSWVNFSHLEGNLSDPCGPNRTELGGSDRLCPSAGSPSMITAIIIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDLRTPRNAKIINICNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPILIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETTPLP
UniProt	P79350
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3041
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL299460
Molecular formula	C17H25NO2
IUPAC name	10-(dimethylamino)-9-(hydroxymethyl)-1-methyltricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol
Molecular weight	275.392
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	2.6
Synonyms	BDBM50050477 10-Dimethylamino-9-hydroxymethyl-1-methyl-tricyclo[7.3.1.02,7]trideca-2,4,6-trien-4-ol
Inchi Key	DYPNTTBEDJXBAY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H25NO2/c1-16-7-6-15(18(2)3)17(10-16,11-19)9-12-4-5-13(20)8-14(12)16/h4-5,8,15,19-20H,6-7,9-11H2,1-3H3
PubChem CID	44301963
ChEMBL	CHEMBL299460
IUPHAR	N/A
BindingDB	50050477
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	830.0 nM	PMID8642554	BindingDB,ChEMBL
Ki	870.0 nM	PMID8642554	ChEMBL

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