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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL334529
Molecular formula	C24H33NO3S
IUPAC name	6-[(4-methoxyphenyl)sulfonylmethyl]-N,N-dipropyl-1,2,3,4-tetrahydronaphthalen-2-amine
Molecular weight	415.592
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	5.2
Synonyms	L014165 6-((4-methoxyphenylsulfonyl)methyl)-N,N-dipropyl-1,2,3,4-tetrahydronaphthalen-2-amine LS-94167 BDBM50240797 GR-218231 [6-(4-Methoxy-benzenesulfonylmethyl)-1,2,3,4-tetrahydro-naphthalen-2-yl]-dipropyl-amine [ Show all ]
Inchi Key	HUXFXXWYIRBVJR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H33NO3S/c1-4-14-25(15-5-2)22-9-8-20-16-19(6-7-21(20)17-22)18-29(26,27)24-12-10-23(28-3)11-13-24/h6-7,10-13,16,22H,4-5,8-9,14-15,17-18H2,1-3H3
PubChem CID	24840389
ChEMBL	CHEMBL334529
IUPHAR	N/A
BindingDB	50240797
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
124728	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
124730	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
124727	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
124721	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
124723	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
555972	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
124722	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
124720	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
124729	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
124724	Alpha-2A adrenergic receptor	P22909	Adra2a	Rattus norvegicus (Rat)	450
124718	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
124726	D(1B) dopamine receptor	P21918	DRD5	Homo sapiens (Human)	477
124716	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
555973	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
124717	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
124719	D(3) dopamine receptor	P19020	Drd3	Rattus norvegicus (Rat)	446
124725	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467

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