You can:
Name | Metabotropic glutamate receptor 8 |
---|---|
Species | Rattus norvegicus (Rat) |
Gene | Grm8 |
Synonym | GLUR8 glutamate receptor Gprc1h mGlu8 receptor mGluR8 [ Show all ] |
Disease | N/A for non-human GPCRs |
Length | 908 |
Amino acid sequence | MVCEGKRLASCPCFFLLTAKFYWILTMMQRTHSQEYAHSIRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKERCPGYIGLCPRMVTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQINNKSTEYKIIGHWTNQLHLKVEDMQWANREHTHPASVCSLPCKPGERKKTVKGVPCCWHCERCEGYNYQVDELSCELCPLDQRPNINRTGCQRIPIIKLEWHSPWAVVPVFIAILGIIATTFVIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYSITFLMIAAPDTIICSFRRIFLGLGMCFSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLVITFSLISVQLLGVFVWFVVDPPHTIIDYGEQRTLDPENARGVLKCDISDLSLICSLGYSILLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIIWLAFIPIFFGTAQSAEKMYIQTTTLTVSMSLSASVSLGMLYMPKVYIIIFHPEQNVQKRKRSFKAVVTAATMQSKLIQKGNDRPNGEVKSELCESLETNTSSTKTTYISYSNHSI |
UniProt | P70579 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL2718 |
IUPHAR | 296 |
DrugBank | N/A |
You can:
GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
---|---|---|---|---|---|---|
557352 | US9212196, Derivative 9 | C13H16Cl2NO8P | 416.144 | 9 / 5 | -2.6 | Yes |
535968 | CHEMBL3974450 | C13H16Cl2NO8P | 416.144 | 9 / 5 | -2.6 | Yes |
535988 | AC1N0YGA | C3H7NO4S | 153.152 | 5 / 2 | -4.7 | Yes |
557607 | US9212196, Derivative 29 | C14H20NO8P | 361.287 | 9 / 5 | -3.4 | Yes |
536279 | CHEMBL3967637 | C14H20NO8P | 361.287 | 9 / 5 | -3.4 | Yes |
12910 | VU 0361737 | C13H11ClN2O2 | 262.693 | 3 / 1 | 2.6 | Yes |
536574 | LSP4-2022 | C13H18NO8P | 347.26 | 9 / 5 | -3.8 | Yes |
522264 | CHEMBL3786667 | C8H11NO6 | 217.177 | 7 / 4 | -4.0 | Yes |
522271 | CHEMBL3787264 | C8H11NO6 | 217.177 | 7 / 4 | -4.0 | Yes |
522276 | CHEMBL3786026 | C8H11NO6 | 217.177 | 7 / 4 | -4.0 | Yes |
522284 | CHEMBL3786938 | C8H11NO6 | 217.177 | 7 / 4 | -4.0 | Yes |
33523 | CHEMBL2179631 | C28H27NO5 | 457.526 | 5 / 1 | 4.8 | Yes |
536924 | CID 57689797 | C3H8NO6P | 185.072 | 6 / 3 | -4.5 | Yes |
558419 | US9212196, Derivative 32 | C14H17F3NO8P | 415.258 | 12 / 4 | -2.1 | No |
536938 | CHEMBL3910941 | C14H17F3NO8P | 415.258 | 12 / 4 | -2.1 | No |
536963 | CHEMBL3898023 | C14H19FNO9P | 395.276 | 11 / 5 | -3.8 | No |
558444 | US9212196, Derivative 6 | C14H19FNO9P | 395.276 | 11 / 5 | -3.8 | No |
42849 | MolPort-000-743-361 | C7H14NO6P | 239.164 | 6 / 3 | -4.2 | Yes |
42850 | AC1MWWXC | C7H14NO6P | 239.164 | 7 / 4 | -4.8 | Yes |
42854 | CHEMBL1089515 | C7H14NO6P | 239.164 | 7 / 4 | -4.8 | Yes |
537085 | CHEMBL3969216 | C14H19ClNO9P | 411.728 | 10 / 5 | -3.2 | Yes |
558599 | US9212196, Derivative 7 | C14H19ClNO9P | 411.728 | 10 / 5 | -3.2 | Yes |
519955 | D-AP4 | C4H10NO5P | 183.1 | 6 / 4 | -5.5 | Yes |
537400 | 2-amino-4-phosphonobutanoic acid | C4H10NO5P | 183.1 | 6 / 4 | -5.5 | Yes |
57283 | L-AP4 | C4H10NO5P | 183.1 | 6 / 4 | -5.5 | Yes |
62857 | CHEMBL396319 | C11H14NO5P | 271.209 | 6 / 4 | -3.3 | Yes |
62866 | CHEMBL392420 | C11H14NO5P | 271.209 | 6 / 4 | -3.3 | Yes |
537500 | CHEMBL3980977 | C14H17F3NO7P | 399.259 | 11 / 4 | -2.4 | No |
559218 | US9212196, Derivative 33 | C14H17F3NO7P | 399.259 | 11 / 4 | -2.4 | No |
537525 | (RS)-MCPG | C10H11NO4 | 209.201 | 5 / 3 | -2.0 | Yes |
537632 | CHEMBL3895389 | C14H20NO8P | 361.287 | 9 / 4 | -3.3 | Yes |
559390 | US9212196, Derivative 31 | C14H20NO8P | 361.287 | 9 / 4 | -3.3 | Yes |
559476 | US9212196, Derivative 19 | C15H22NO9P | 391.313 | 10 / 5 | -3.5 | Yes |
537685 | CHEMBL3941586 | C15H22NO9P | 391.313 | 10 / 5 | -3.5 | Yes |
82271 | CHEMBL3298273 | C15H13FN2O2 | 272.279 | 4 / 1 | 2.1 | Yes |
85068 | CHEMBL1076865 | C7H13ClNO6P | 273.606 | 7 / 4 | -4.1 | Yes |
100373 | SCHEMBL8239107 | C8H14NO6P | 251.175 | 7 / 3 | -4.7 | Yes |
553767 | MSOP | C4H10NO6P | 199.099 | 7 / 4 | -5.0 | Yes |
109296 | (2S,1'S,2'S)-2-(carboxycyclopropyl)glycine | C6H9NO4 | 159.141 | 5 / 3 | -3.4 | Yes |
110382 | BDBM50100942 | C5H9NO5 | 163.129 | 5 / 3 | -3.4 | Yes |
110385 | 2485-33-8 | C5H9NO5 | 163.129 | 6 / 4 | -4.1 | Yes |
538734 | CHEMBL3912541 | C15H22NO8P | 375.314 | 9 / 5 | -3.1 | Yes |
560798 | US9212196, Derivative 10 | C15H22NO8P | 375.314 | 9 / 5 | -3.1 | Yes |
560845 | CHEMBL404886 | C25H16FN5O2 | 437.434 | 6 / 2 | 3.6 | Yes |
538882 | CHEMBL3927149 | C14H18NO10P | 391.269 | 11 / 6 | -4.3 | No |
560945 | US9212196, Derivative 23 | C14H18NO10P | 391.269 | 11 / 6 | -4.3 | No |
538899 | CHEMBL3913188 | C14H19FNO8P | 379.277 | 10 / 4 | -3.2 | Yes |
560963 | US9212196, Derivative 34 | C14H19FNO8P | 379.277 | 10 / 4 | -3.2 | Yes |
553881 | MAP4 | C5H12NO5P | 197.127 | 6 / 4 | -4.6 | Yes |
128446 | L-PHOSPHINOTHRICIN | C5H12NO4P | 181.128 | 5 / 3 | -5.0 | Yes |
130322 | demethylphosphinothricin | C4H10NO4P | 167.101 | 5 / 3 | -5.1 | Yes |
553950 | cppg | C11H14NO5P | 271.209 | 6 / 4 | -3.1 | Yes |
135011 | (S)-3,4-DCPG | C10H9NO6 | 239.183 | 7 / 4 | -2.7 | Yes |
561523 | US9212196, Derivative 28 | C13H16F2NO8P | 383.241 | 11 / 5 | -3.6 | No |
539423 | CHEMBL3896442 | C13H16F2NO8P | 383.241 | 11 / 5 | -3.6 | No |
539453 | CHEMBL3905370 | C13H18NO7PS | 363.321 | 9 / 5 | -3.3 | Yes |
561553 | US9212196, Derivative 26 | C13H18NO7PS | 363.321 | 9 / 5 | -3.3 | Yes |
138528 | CHEMBL1093612 | C9H18NO7P | 283.217 | 8 / 5 | -5.1 | Yes |
539800 | CHEMBL3982807 | C15H22NO10P | 407.312 | 11 / 5 | -3.9 | No |
561930 | US9212196, Derivative 4 | C15H22NO10P | 407.312 | 11 / 5 | -3.9 | No |
158295 | (RS)-PPG | C8H10NO5P | 231.144 | 6 / 4 | -3.7 | Yes |
181956 | CHEMBL197976 | C5H10NO5P | 195.111 | 6 / 4 | -4.7 | Yes |
181966 | CHEMBL199626 | C5H10NO5P | 195.111 | 6 / 4 | -4.7 | Yes |
181969 | CHEMBL442076 | C5H10NO5P | 195.111 | 6 / 4 | -4.7 | Yes |
187014 | CHEMBL140197 | C6H9NO5 | 175.14 | 6 / 4 | -3.9 | Yes |
187025 | CHEMBL357043 | C6H9NO5 | 175.14 | 6 / 4 | -3.9 | Yes |
540899 | CHEMBL3917132 | C15H20NO11P | 421.295 | 12 / 6 | -4.3 | No |
563228 | US9212196, Derivative 18 | C15H20NO11P | 421.295 | 12 / 6 | -4.3 | No |
189227 | CHEMBL2373733 | C21H16ClN3O3 | 393.827 | 4 / 1 | 2.6 | Yes |
541003 | CHEMBL3935255 | C14H20NO9P | 377.286 | 10 / 5 | -3.9 | Yes |
563328 | US9212196, Derivative 3 | C14H20NO9P | 377.286 | 10 / 5 | -3.9 | Yes |
201020 | Dcg-IV | C7H9NO6 | 203.15 | 7 / 4 | -4.3 | Yes |
213638 | VU0366037-2 | C19H13Cl2N3O2 | 386.232 | 3 / 2 | 4.1 | Yes |
222189 | CHEMBL1204419 | C9H17ClNO7P | 317.659 | 8 / 6 | N/A | No |
550722 | CHEMBL3894544 | C12H19NO9P2 | 383.23 | 10 / 6 | -5.2 | No |
564460 | US9212196, Derivative 14 | C12H19NO9P2 | 383.23 | 10 / 6 | -5.2 | No |
542101 | CHEMBL3890165 | C14H17F3NO9P | 431.257 | 13 / 5 | -2.7 | No |
564553 | US9212196, Derivative 20 | C14H17F3NO9P | 431.257 | 13 / 5 | -2.7 | No |
542300 | CHEMBL3966924 | C14H19N2O11P | 422.283 | 12 / 5 | -4.0 | No |
564755 | US9212196, Derivative 5 | C14H19N2O11P | 422.283 | 12 / 5 | -4.0 | No |
542744 | MPPG | C9H12NO5P | 245.171 | 6 / 4 | -3.5 | Yes |
542781 | (2s)-2-amino-4-sulfinobutanoic acid | C4H9NO4S | 167.179 | 6 / 3 | -3.8 | Yes |
259128 | CHEMBL1092315 | C9H16NO8P | 297.2 | 9 / 5 | -5.3 | Yes |
543034 | CHEMBL3909874 | C14H19ClNO8P | 395.729 | 9 / 4 | -2.7 | Yes |
565523 | US9212196, Derivative 35 | C14H19ClNO8P | 395.729 | 9 / 4 | -2.7 | Yes |
265337 | CHEMBL2179646 | C26H22ClNO3 | 431.916 | 3 / 1 | 5.6 | No |
543558 | CHEMBL3982457 | C14H18NO7P | 343.272 | 8 / 5 | -3.5 | Yes |
565981 | US9212196, Derivative 11 | C14H18NO7P | 343.272 | 8 / 5 | -3.5 | Yes |
282813 | CHEMBL1089852 | C6H12NO6P | 225.137 | 7 / 4 | -4.7 | Yes |
566050 | BDBM50314796 | C7H12NO6P | 237.148 | 7 / 4 | -2.1 | Yes |
292330 | CHEMBL2179629 | C24H18ClNO4S | 451.921 | 5 / 1 | 5.3 | No |
310567 | CHEMBL243925 | C4H10NO4PS | 199.161 | 6 / 4 | -3.8 | Yes |
544479 | MDMA | C11H15NO2 | 193.246 | 3 / 1 | 2.2 | Yes |
316449 | CID 46197877 | C9H16NO6P | 265.202 | 7 / 3 | -4.4 | Yes |
319662 | CID 46197879 | C6H12NO7P | 241.136 | 8 / 5 | -5.3 | Yes |
323922 | 61350-00-3 | C12H9ClN2O | 232.667 | 2 / 1 | 2.6 | Yes |
544826 | CHEMBL3896964 | C13H20NO7P | 333.277 | 8 / 5 | -4.1 | Yes |
567540 | US9212196, Derivative 13 | C13H20NO7P | 333.277 | 8 / 5 | -4.1 | Yes |
567705 | US9212196, Derivative 21 | C14H17F3NO8P | 415.258 | 12 / 5 | -3.0 | No |
544957 | CHEMBL3918221 | C14H17F3NO8P | 415.258 | 12 / 5 | -3.0 | No |
zhanglabzhanggroup.org | +65-6601-1241 | Computing 1, 13 Computing Drive, Singapore 117417