Zhang Lab

National University of Singapore

Home Research COVID-19 Services Publications People Teaching Job Opening News Forum Lab Only

Online Services

●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	L-PHOSPHINOTHRICIN
Molecular formula	C5H12NO4P
IUPAC name	(2S)-2-amino-4-[hydroxy(methyl)phosphoryl]butanoic acid
Molecular weight	181.128
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	-5.0
Synonyms	2-AMINO-4-(HYDROXYMETHYL-PHOSPHINYL)BUTANOIC ACID CHEMBL145114 PPQ 72P470U27C L-2-Amino-4-(hydroxymethylphosphinyl)butanoate UNII-C8W4FP6BTY component IAJOBQBIJHVGMQ-BYPYZUCNSA-N (S)-Phosphinothricin@CRLF35597-44-5 C04650 35597-44-5 CHEMBL535153 SCHEMBL21986 (2S)-2-amino-4-[hydroxy(methyl)phosphoryl]butanoic acid AC1L3MFS L-Glufosinate ZINC902209 1fpy Phosphinothricine IAJOBQBIJHVGMQ-BYPYZUCNSA-N UNII-72P470U27C (S)-2-Amino-4-(hydroxy-methyl-phosphinoyl)-butyric acid; hydrochloride BDBM50174527 L-homoalanin-4-yl(methyl)phosphinic acid [ Show all ]
Inchi Key	IAJOBQBIJHVGMQ-BYPYZUCNSA-N
Inchi ID	InChI=1S/C5H12NO4P/c1-11(9,10)3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10)/t4-/m0/s1
PubChem CID	91619
ChEMBL	CHEMBL145114
IUPHAR	N/A
BindingDB	50174527
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
128449	Metabotropic glutamate receptor 4	P31423	Grm4	Rattus norvegicus (Rat)	912
128448	Metabotropic glutamate receptor 6	P35349	Grm6	Rattus norvegicus (Rat)	871
128447	Metabotropic glutamate receptor 7	P35400	Grm7	Rattus norvegicus (Rat)	915
128446	Metabotropic glutamate receptor 8	P70579	Grm8	Rattus norvegicus (Rat)	908

zhanglabzhanggroup.org | +65-6601-1241 | Computing 1, 13 Computing Drive, Singapore 117417