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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	2485-33-8
Molecular formula	C5H9NO5
IUPAC name	(2S,4R)-2-amino-4-hydroxypentanedioic acid
Molecular weight	163.129
Hydrogen bond acceptor	6
Hydrogen bond donor	4
XlogP	-4.1
Synonyms	(4R)-4-Hydroxy-L-glutamic acid, >=98.0% (TLC) CHEBI:21285 H-(2S,4R)--Hydroxy-Glu-OH SCHEMBL5819946 (2S,4R)-4-Hydroxyglutamic Acid CTK8F1736 H-(2S,4R)-\|A-Hydroxy-Glu-OH (2S,4R)-gamma-Hydroxyglutamic acid AKOS006271402 erythro-4-hydroxy-L-glutamic acid L-erythro-4-hydroxyglutamic acid (2S,4R)-2-amino-4-hydroxypentanedioic acid (4S)-4-hydroxy-L-glutamic acid H-(2S,4R)-Gamma-Hydroxy-Glu-OH ZINC895967 (2S,4R)-g-4-Hydroxy-L-glutamic Acid 7033AH DTXSID90331532 J-015700 (4R)-4-Hydroxy-L-glutamic acid C05947 FT-0669646 L-Glutamic acid,4-hydroxy-,(4R)- (2S,4R)-4-Hydroxy-L-glutamic Acid CHEMBL371946 H-(2S,4R)-Glu(g-OH)-OH (2S,4R)-gamma-Hydroxy-glutamic acid AC1L9A2D erythro-(4R)-4-Hydroxy-L-glutamic acid L-erythro-4-Hydroxyglutamate [ Show all ]
Inchi Key	HBDWQSHEVMSFGY-STHAYSLISA-N
Inchi ID	InChI=1S/C5H9NO5/c6-2(4(8)9)1-3(7)5(10)11/h2-3,7H,1,6H2,(H,8,9)(H,10,11)/t2-,3+/m0/s1
PubChem CID	440854
ChEMBL	CHEMBL371946
IUPHAR	N/A
BindingDB	50100941
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
110387	Metabotropic glutamate receptor 1	P23385	Grm1	Rattus norvegicus (Rat)	1199
110386	Metabotropic glutamate receptor 2	P31421	Grm2	Rattus norvegicus (Rat)	872
110385	Metabotropic glutamate receptor 8	P70579	Grm8	Rattus norvegicus (Rat)	908

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