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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3787264
Molecular formula	C8H11NO6
IUPAC name	(1R,2S)-1-[(2S)-2-amino-2-carboxyethyl]cyclopropane-1,2-dicarboxylic acid
Molecular weight	217.177
Hydrogen bond acceptor	7
Hydrogen bond donor	4
XlogP	-4.0
Synonyms	BDBM50159150 J3.605.574J (1R)-1-[(S)-2-Amino-3-oxo-3-hydroxypropyl]cyclopropane-1alpha,2beta-dicarboxylic acid
Inchi Key	BHSHZTNHTMTQFY-PDJPSNROSA-N
Inchi ID	InChI=1S/C8H11NO6/c9-4(6(12)13)2-8(7(14)15)1-3(8)5(10)11/h3-4H,1-2,9H2,(H,10,11)(H,12,13)(H,14,15)/t3-,4+,8-/m1/s1
PubChem CID	127030385
ChEMBL	CHEMBL3787264
IUPHAR	N/A
BindingDB	50159150
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
522267	Metabotropic glutamate receptor 1	P23385	Grm1	Rattus norvegicus (Rat)	1199
522270	Metabotropic glutamate receptor 2	P31421	Grm2	Rattus norvegicus (Rat)	872
558018	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
522268	Metabotropic glutamate receptor 3	P31422	Grm3	Rattus norvegicus (Rat)	879
522269	Metabotropic glutamate receptor 4	P31423	Grm4	Rattus norvegicus (Rat)	912
522272	Metabotropic glutamate receptor 5	P31424	Grm5	Rattus norvegicus (Rat)	1203
522274	Metabotropic glutamate receptor 6	P35349	Grm6	Rattus norvegicus (Rat)	871
522273	Metabotropic glutamate receptor 7	P35400	Grm7	Rattus norvegicus (Rat)	915
522271	Metabotropic glutamate receptor 8	P70579	Grm8	Rattus norvegicus (Rat)	908

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