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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2373733
Molecular formula	C21H16ClN3O3
IUPAC name	N-[3-chloro-4-[(1S,2R,6R,7R)-3,5-dioxo-4-azatricyclo[5.2.1.02,6]dec-8-en-4-yl]phenyl]pyridine-2-carboxamide
Molecular weight	393.827
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	2.6
Synonyms	N/A
Inchi Key	LJUABYFUJVRUSJ-FVEFGIFQSA-N
Inchi ID	InChI=1S/C21H16ClN3O3/c22-14-10-13(24-19(26)15-3-1-2-8-23-15)6-7-16(14)25-20(27)17-11-4-5-12(9-11)18(17)21(25)28/h1-8,10-12,17-18H,9H2,(H,24,26)/t11-,12+,17-,18-/m1/s1
PubChem CID	90661779
ChEMBL	CHEMBL2373733
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
189232	Metabotropic glutamate receptor 1	P23385	Grm1	Rattus norvegicus (Rat)	1199
189235	Metabotropic glutamate receptor 2	P31421	Grm2	Rattus norvegicus (Rat)	872
189230	Metabotropic glutamate receptor 3	P31422	Grm3	Rattus norvegicus (Rat)	879
189228	Metabotropic glutamate receptor 4	Q14833	GRM4	Homo sapiens (Human)	912
189229	Metabotropic glutamate receptor 4	P31423	Grm4	Rattus norvegicus (Rat)	912
189231	Metabotropic glutamate receptor 5	P31424	Grm5	Rattus norvegicus (Rat)	1203
189234	Metabotropic glutamate receptor 6	O15303	GRM6	Homo sapiens (Human)	877
189233	Metabotropic glutamate receptor 7	P35400	Grm7	Rattus norvegicus (Rat)	915
189227	Metabotropic glutamate receptor 8	P70579	Grm8	Rattus norvegicus (Rat)	908

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