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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	D-AP4
Molecular formula	C4H10NO5P
IUPAC name	(2R)-2-amino-4-phosphonobutanoic acid
Molecular weight	183.1
Hydrogen bond acceptor	6
Hydrogen bond donor	4
XlogP	-5.5
Synonyms	(r)-2-amino-4-phosphonobutyric acid BDBM82006 D-(-)-2-Amino-4-phosphonobutyric acid Lopac-A-1910 PDSP2_000359 C-55168 D0G7TT NCGC00015041-01 SR-01000597691-1 (2R)-2-amino-4-phosphonobutanoic acid API0009835 CTK2I0929 GTPL1443 NCGC00024467-01 UNII-H8B59H10OK component DDOQBQRIEWHWBT-GSVOUGTGSA-N BN0083 M01255 SCHEMBL12648443 AC1LT3KN FCH3604711 NCGC00015041-02 Tocris-0101 (R)-2-Amino-4-phosphonobutanoic acid B6201 d(-)-2-amino-4-phosphonobutyric acid I04-1600 PDSP1_000361 ZINC1656225 78739-01-2 Butanoic acid, 2-amino-4-phosphono-, (2R)- D-APB MolPort-004-956-473 SR-01000597691 AKOS024456336 CHEMBL1319383 FT-0772107 NCGC00024466-01 Tocris-0102 [ Show all ]
Inchi Key	DDOQBQRIEWHWBT-GSVOUGTGSA-N
Inchi ID	InChI=1S/C4H10NO5P/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H2,8,9,10)/t3-/m1/s1
PubChem CID	1550579
ChEMBL	CHEMBL1319383
IUPHAR	1443
BindingDB	82006
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
519954	Metabotropic glutamate receptor 4	P31423	Grm4	Rattus norvegicus (Rat)	912
519957	Metabotropic glutamate receptor 6	P35349	Grm6	Rattus norvegicus (Rat)	871
519956	Metabotropic glutamate receptor 7	P35400	Grm7	Rattus norvegicus (Rat)	915
519955	Metabotropic glutamate receptor 8	P70579	Grm8	Rattus norvegicus (Rat)	908
553523	Metabotropic glutamate receptor 8	O00222	GRM8	Homo sapiens (Human)	908
57271	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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