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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2179629
Molecular formula	C24H18ClNO4S
IUPAC name	2-chloro-5-[3-[(2-cyclopropyl-3-oxo-1,2-benzothiazol-6-yl)oxymethyl]phenyl]benzoic acid
Molecular weight	451.921
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	5.3
Synonyms	SCHEMBL787213 BDBM50398744
Inchi Key	RBQZSTHTHNKFHW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H18ClNO4S/c25-21-9-4-16(11-20(21)24(28)29)15-3-1-2-14(10-15)13-30-18-7-8-19-22(12-18)31-26(23(19)27)17-5-6-17/h1-4,7-12,17H,5-6,13H2,(H,28,29)
PubChem CID	53390677
ChEMBL	CHEMBL2179629
IUPHAR	N/A
BindingDB	50398744
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
292332	Metabotropic glutamate receptor 1	P23385	Grm1	Rattus norvegicus (Rat)	1199
292324	Metabotropic glutamate receptor 2	P31421	Grm2	Rattus norvegicus (Rat)	872
566406	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
292326	Metabotropic glutamate receptor 3	P31422	Grm3	Rattus norvegicus (Rat)	879
292327	Metabotropic glutamate receptor 4	P31423	Grm4	Rattus norvegicus (Rat)	912
292328	Metabotropic glutamate receptor 5	P31424	Grm5	Rattus norvegicus (Rat)	1203
292331	Metabotropic glutamate receptor 6	P35349	Grm6	Rattus norvegicus (Rat)	871
292325	Metabotropic glutamate receptor 7	P35400	Grm7	Rattus norvegicus (Rat)	915
292330	Metabotropic glutamate receptor 8	P70579	Grm8	Rattus norvegicus (Rat)	908

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