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Name | Prostaglandin F2-alpha receptor |
---|---|
Species | Bos taurus (Bovine) |
Gene | PTGFR |
Synonym | PGF receptor PGF2-alpha receptor Prostanoid FP receptor |
Disease | N/A for non-human GPCRs |
Length | 362 |
Amino acid sequence | MSTNSSIQPVSPESELLSNTTCQLEEDLSISFSIIFMTVGILSNSLAIAILMKAYQRFRQKYKSSFLLLASALVITDFFGHLINGTIAVFVYASDKDWIYFDKSNILCSIFGICMVFSGLCPLFLGSLMAIERCIGVTKPIFHSTKITTKHVKMMLSGVCFFAVFVALLPILGHRDYKIQASRTWCFYKTDEIKDWEDRFYLLLFAFLGLLALGISFVCNAITGISLLKVKFRSQQHRQGRSHHFEMVIQLLGIMCVSCICWSPFLVTMASIGMNIQDFKDSCERTLFTLRMATWNQILDPWVYILLRKAVLRNLYVCTRRCCGVHVISLHVWELSSIKDSLKVAAISDLPVTEKVTQQTST |
UniProt | P37289 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL4820 |
IUPHAR | N/A |
DrugBank | N/A |
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GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
---|---|---|---|---|---|---|
30386 | CHEMBL433752 | C22H29ClO6 | 424.918 | 6 / 3 | 3.1 | Yes |
30388 | CHEMBL183193 | C22H29ClO6 | 424.918 | 6 / 3 | 3.1 | Yes |
73629 | 16-phenoxy tetranor Prostaglandin F2alpha | C22H30O6 | 390.476 | 6 / 4 | 2.1 | Yes |
78744 | CHEMBL88275 | C25H36O5 | 416.558 | 5 / 4 | 3.6 | Yes |
78746 | CHEMBL2114230 | C25H36O5 | 416.558 | 5 / 4 | 3.6 | Yes |
83129 | 17-phenyl-trinor-PGE2 | C23H30O5 | 386.488 | 5 / 3 | 2.8 | Yes |
96125 | Lanatoprost | C26H40O5 | 432.601 | 5 / 3 | 4.3 | Yes |
96130 | CHEMBL364375 | C26H40O5 | 432.601 | 5 / 3 | 4.3 | Yes |
96139 | 15(S)-Latanoprost | C26H40O5 | 432.601 | 5 / 3 | 4.3 | Yes |
100244 | 15(R)-Prostaglandin E1 | C20H34O5 | 354.487 | 5 / 3 | 3.2 | Yes |
100267 | 8-iso Prostaglandin E1 | C20H34O5 | 354.487 | 5 / 3 | 3.2 | Yes |
109809 | N-Nitrosodithiazine | C3H6N2OS2 | 150.214 | 5 / 0 | 1.6 | Yes |
117251 | CHEMBL489109 | C21H29ClO7 | 428.906 | 7 / 4 | 2.1 | Yes |
117253 | CHEMBL491474 | C21H29ClO7 | 428.906 | 7 / 4 | 2.1 | Yes |
119553 | Latanoprost acid | C23H34O5 | 390.52 | 5 / 4 | 3.1 | Yes |
119555 | 5-trans Latanoprost (free acid) | C23H34O5 | 390.52 | 5 / 4 | 3.1 | Yes |
127176 | CHEMBL491475 | C21H30O7 | 394.464 | 7 / 4 | 1.4 | Yes |
127177 | CHEMBL523143 | C21H30O7 | 394.464 | 7 / 4 | 1.4 | Yes |
139259 | BDBM85347 | C25H37N3O5 | 459.587 | 6 / 4 | 1.7 | Yes |
141379 | CHEMBL184249 | C22H30O6 | 390.476 | 6 / 3 | 2.5 | Yes |
141380 | CHEMBL363946 | C22H30O6 | 390.476 | 6 / 3 | 2.5 | Yes |
142879 | CHEMBL1910324 | C45H71N13O13 | 1002.14 | 16 / 15 | -5.8 | No |
150770 | 17-Phenyl trinor Pgf2alpha-Ipr | C26H38O5 | 430.585 | 5 / 3 | 3.8 | Yes |
173563 | CHEMBL422242 | C26H38O5 | 430.585 | 5 / 3 | 3.9 | Yes |
173564 | CHEMBL2114229 | C26H38O5 | 430.585 | 5 / 3 | 3.9 | Yes |
193621 | 5-trans U-46619 | C21H34O4 | 350.499 | 4 / 2 | 3.9 | Yes |
193626 | U-46619 | C21H34O4 | 350.499 | 4 / 2 | 3.9 | Yes |
200089 | CHEMBL185466 | C23H29F3O6 | 458.474 | 9 / 3 | 3.4 | Yes |
200092 | CHEMBL186192 | C23H29F3O6 | 458.474 | 9 / 3 | 3.4 | Yes |
203633 | CHEMBL2114224 | C23H30IN3O5 | 555.413 | 7 / 4 | 4.3 | No |
203634 | CHEMBL90450 | C23H30IN3O5 | 555.413 | 7 / 4 | 4.3 | No |
207788 | CHEMBL185484 | C26H35F3O6 | 500.555 | 9 / 3 | 4.1 | No |
213411 | CHEMBL88974 | C23H31N3O5 | 429.517 | 7 / 4 | 3.6 | Yes |
242066 | CHEMBL315519 | C23H31N3O6 | 445.516 | 8 / 5 | 3.3 | Yes |
243760 | CHEMBL273444 | C22H30O6 | 390.476 | 6 / 3 | 2.5 | Yes |
243762 | CHEMBL182117 | C22H30O6 | 390.476 | 6 / 3 | 2.5 | Yes |
268571 | AC1L1FGW | C23H28O6 | 400.471 | 6 / 2 | 1.3 | Yes |
271226 | CHEMBL12114 | C20H34O5 | 354.487 | 5 / 4 | 2.7 | Yes |
271232 | 8-Iso-15(R)-prostaglandin F2alpha | C20H34O5 | 354.487 | 5 / 4 | 2.7 | Yes |
271238 | MLS003107056 | C20H34O5 | 354.487 | 5 / 4 | 2.7 | Yes |
271245 | dinoprost | C20H34O5 | 354.487 | 5 / 4 | 2.7 | Yes |
272172 | CHEMBL422418 | C22H29N3O7 | 447.488 | 9 / 5 | 2.6 | Yes |
328088 | 87893-54-7 | C20H30O4 | 334.456 | 4 / 2 | 3.9 | Yes |
329361 | CHEMBL264554 | C19H32O5 | 340.46 | 5 / 3 | 2.6 | Yes |
329363 | CHEMBL360869 | C19H32O5 | 340.46 | 5 / 3 | 2.6 | Yes |
343370 | 60325-46-4 | C23H31NO7S | 465.561 | 7 / 3 | 1.5 | Yes |
356499 | cloprostenol | C22H29ClO6 | 424.918 | 6 / 4 | 2.7 | Yes |
356506 | 7-{2-[4-(3-chlorophenoxy)-3-hydroxybut-1-en-1-yl]-3,5-dihydroxycyclopentyl}hept-5-enoic acid | C22H29ClO6 | 424.918 | 6 / 4 | 2.7 | Yes |
370778 | CHEMBL184264 | C22H29ClO6 | 424.918 | 6 / 3 | 3.1 | Yes |
370780 | CHEMBL360862 | C22H29ClO6 | 424.918 | 6 / 3 | 3.1 | Yes |
384215 | (+)-fluprostenol | C23H29F3O6 | 458.474 | 9 / 4 | 2.9 | Yes |
390112 | Prostaglandin E2 | C20H32O5 | 352.471 | 5 / 3 | 2.8 | Yes |
390127 | 8-iso PROSTAGLANDIN E2 | C20H32O5 | 352.471 | 5 / 3 | 2.8 | Yes |
395157 | CHEMBL521964 | C23H31F3O6 | 460.49 | 9 / 4 | 3.0 | Yes |
395159 | CHEMBL491667 | C23H31F3O6 | 460.49 | 9 / 4 | 3.0 | Yes |
403523 | Unoprostone isopropyl ester | C25H44O5 | 424.622 | 5 / 2 | 4.9 | Yes |
404461 | 69552-46-1 | C21H34O4 | 350.499 | 4 / 3 | 3.2 | Yes |
404475 | carbacyclin | C21H34O4 | 350.499 | 4 / 3 | 3.2 | Yes |
418200 | CHEMBL363439 | C23H29F3O6 | 458.474 | 9 / 3 | 3.4 | Yes |
418202 | CHEMBL185559 | C23H29F3O6 | 458.474 | 9 / 3 | 3.4 | Yes |
422984 | BW A868C | C25H37N3O5 | 459.587 | 6 / 3 | 1.7 | Yes |
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