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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	8-iso Prostaglandin E1
Molecular formula	C20H34O5
IUPAC name	7-[3-hydroxy-2-(3-hydroxyoct-1-enyl)-5-oxocyclopentyl]heptanoic acid
Molecular weight	354.487
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	3.2
Synonyms	11alpha,13E,15S]-11,15-Dihydroxy-9-oxoprosta-13-en-1-oic acid AN-10384 7-[3-hydroxy-2-(3-hydroxyoct-1-enyl)-5-oxo-cyclopentyl]heptanoic acid HMS3654H18 AC1L18QG SCHEMBL5303767 21003-46-3 CTK8F7408 7-[3-hydroxy-2-(3-hydroxyoct-1-enyl)-5-oxocyclopentyl]heptanoic acid MCULE-5248179465 119314-69-1 ACMC-20moau 7-[3-hydroxy-2-(3-hydroxyoct-1-enyl)-5-keto-cyclopentyl]enanthic acid HMS3394L11 Prost-13-en-1-oic acid,11,15-dihydroxy-9-oxo-, (11a,13E,15S)-, homopolymer (9CI) [ Show all ]
Inchi Key	GMVPRGQOIOIIMI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)
PubChem CID	214
ChEMBL	N/A
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
100266	Prostaglandin E2 receptor EP3 subtype	P34979	PTGER3	Bos taurus (Bovine)	417
100267	Prostaglandin F2-alpha receptor	P37289	PTGFR	Bos taurus (Bovine)	362

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