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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	15(S)-Latanoprost
Molecular formula	C26H40O5
IUPAC name	propan-2-yl 7-[3,5-dihydroxy-2-(3-hydroxy-5-phenylpentyl)cyclopentyl]hept-5-enoate
Molecular weight	432.601
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	4.3
Synonyms	AN-601 trans Latanoprost 145773-22-4 Isopropyl 7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((R)-3-hydroxy-5-phenylpentyl)cyclopentyl)hept-5-enoate AC1L1GXT propan-2-yl 7-[3,5-dihydroxy-2-(3-hydroxy-5-phenylpentyl)cyclopentyl]hept-5-enoate CTK7J6539 isopropyl 7-[3,5-dihydroxy-2-(3-hydroxy-5-phenyl-pentyl)cyclopentyl]hept-5-enoate AKOS030228257 TRA0064809 HMS3393H11 913258-34-1 KS-00000Z34 [ Show all ]
Inchi Key	GGXICVAJURFBLW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H40O5/c1-19(2)31-26(30)13-9-4-3-8-12-22-23(25(29)18-24(22)28)17-16-21(27)15-14-20-10-6-5-7-11-20/h3,5-8,10-11,19,21-25,27-29H,4,9,12-18H2,1-2H3
PubChem CID	3890
ChEMBL	N/A
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
96134	Prostacyclin receptor	P43119	PTGIR	Homo sapiens (Human)	386
96138	Prostaglandin D2 receptor	Q13258	PTGDR	Homo sapiens (Human)	359
96135	Prostaglandin E2 receptor EP1 subtype	P34995	PTGER1	Homo sapiens (Human)	402
96131	Prostaglandin E2 receptor EP2 subtype	P43116	PTGER2	Homo sapiens (Human)	358
96136	Prostaglandin E2 receptor EP3 subtype	P34979	PTGER3	Bos taurus (Bovine)	417
96137	Prostaglandin E2 receptor EP3 subtype	P43115	PTGER3	Homo sapiens (Human)	390
96132	Prostaglandin E2 receptor EP4 subtype	P35408	PTGER4	Homo sapiens (Human)	488
96133	Prostaglandin F2-alpha receptor	P43088	PTGFR	Homo sapiens (Human)	359
96139	Prostaglandin F2-alpha receptor	P37289	PTGFR	Bos taurus (Bovine)	362

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