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Name | Prostaglandin F2-alpha receptor |
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Species | Bos taurus (Bovine) |
Gene | PTGFR |
Synonym | PGF receptor PGF2-alpha receptor Prostanoid FP receptor |
Disease | N/A for non-human GPCRs |
Length | 362 |
Amino acid sequence | MSTNSSIQPVSPESELLSNTTCQLEEDLSISFSIIFMTVGILSNSLAIAILMKAYQRFRQKYKSSFLLLASALVITDFFGHLINGTIAVFVYASDKDWIYFDKSNILCSIFGICMVFSGLCPLFLGSLMAIERCIGVTKPIFHSTKITTKHVKMMLSGVCFFAVFVALLPILGHRDYKIQASRTWCFYKTDEIKDWEDRFYLLLFAFLGLLALGISFVCNAITGISLLKVKFRSQQHRQGRSHHFEMVIQLLGIMCVSCICWSPFLVTMASIGMNIQDFKDSCERTLFTLRMATWNQILDPWVYILLRKAVLRNLYVCTRRCCGVHVISLHVWELSSIKDSLKVAAISDLPVTEKVTQQTST |
UniProt | P37289 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL4820 |
IUPHAR | N/A |
DrugBank | N/A |
Name | 5-trans U-46619 |
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Molecular formula | C21H34O4 |
IUPAC name | 7-[6-(3-hydroxyoct-1-enyl)-2-oxabicyclo[2.2.1]heptan-5-yl]hept-5-enoic acid |
Molecular weight | 350.499 |
Hydrogen bond acceptor | 4 |
Hydrogen bond donor | 2 |
XlogP | 3.9 |
Synonyms | 330796-58-2 HMS3372C01 7-[3-(3-hydroxyoct-1-enyl)-5-oxabicyclo[2.2.1]heptan-2-yl]hept-5-enoic acid AC1L1KR2 U-46619 [ Show all ] |
Inchi Key | LQANGKSBLPMBTJ-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C21H34O4/c1-2-3-6-9-17(22)12-13-19-18(16-14-20(19)25-15-16)10-7-4-5-8-11-21(23)24/h4,7,12-13,16-20,22H,2-3,5-6,8-11,14-15H2,1H3,(H,23,24) |
PubChem CID | 5618 |
ChEMBL | N/A |
IUPHAR | N/A |
BindingDB | N/A |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand satisfies Lipinski's rule of five. |
Parameter | Value | Reference | Database source |
---|---|---|---|
Ki | 8900.0 nM | PMID9694973 | PDSP |
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