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Name | Prostaglandin F2-alpha receptor |
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Species | Bos taurus (Bovine) |
Gene | PTGFR |
Synonym | PGF receptor PGF2-alpha receptor Prostanoid FP receptor |
Disease | N/A for non-human GPCRs |
Length | 362 |
Amino acid sequence | MSTNSSIQPVSPESELLSNTTCQLEEDLSISFSIIFMTVGILSNSLAIAILMKAYQRFRQKYKSSFLLLASALVITDFFGHLINGTIAVFVYASDKDWIYFDKSNILCSIFGICMVFSGLCPLFLGSLMAIERCIGVTKPIFHSTKITTKHVKMMLSGVCFFAVFVALLPILGHRDYKIQASRTWCFYKTDEIKDWEDRFYLLLFAFLGLLALGISFVCNAITGISLLKVKFRSQQHRQGRSHHFEMVIQLLGIMCVSCICWSPFLVTMASIGMNIQDFKDSCERTLFTLRMATWNQILDPWVYILLRKAVLRNLYVCTRRCCGVHVISLHVWELSSIKDSLKVAAISDLPVTEKVTQQTST |
UniProt | P37289 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL4820 |
IUPHAR | N/A |
DrugBank | N/A |
Name | 87893-54-7 |
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Molecular formula | C20H30O4 |
IUPAC name | 7-[5-(3-hydroxyoctylidene)-4-oxocyclopent-2-en-1-yl]hept-5-enoic acid |
Molecular weight | 334.456 |
Hydrogen bond acceptor | 4 |
Hydrogen bond donor | 2 |
XlogP | 3.9 |
Synonyms | 7-[5-(3-hydroxyoctylidene)-4-oxocyclopent-2-en-1-yl]hept-5-enoic acid AC1L1ET8 I"12-PGJ2 (I"12-Prostaglandin J2) |
Inchi Key | TUXFWOHFPFBNEJ-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C20H30O4/c1-2-3-6-10-17(21)13-14-18-16(12-15-19(18)22)9-7-4-5-8-11-20(23)24/h4,7,12,14-17,21H,2-3,5-6,8-11,13H2,1H3,(H,23,24) |
PubChem CID | 2937 |
ChEMBL | N/A |
IUPHAR | N/A |
BindingDB | 82213 |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand satisfies Lipinski's rule of five. |
Parameter | Value | Reference | Database source |
---|---|---|---|
Ki | 2500.0 nM | PMID9694973 | PDSP,BindingDB |
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