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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	U-46619
Molecular formula	C21H34O4
IUPAC name	(Z)-7-[(1R,4S,5S)-6-[(E,3S)-3-hydroxyoct-1-enyl]-2-oxabicyclo[2.2.1]heptan-5-yl]hept-5-enoic acid
Molecular weight	350.499
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	3.9
Synonyms	7-[6-(3-Hydroxy-oct-1-enyl)-2-oxa-bicyclo[2.2.1]hept-5-yl]-hept-5-enoic acid (Z)-7-[(S)-6-((E)-(S)-3-Hydroxy-oct-1-enyl)-2-oxa-bicyclo[2.2.1]hept-5-yl]-hept-5-enoic acid BDBM50018531 CHEMBL73010
Inchi Key	LQANGKSBLPMBTJ-YDMCPATHSA-N
Inchi ID	InChI=1S/C21H34O4/c1-2-3-6-9-17(22)12-13-19-18(16-14-20(19)25-15-16)10-7-4-5-8-11-21(23)24/h4,7,12-13,16-20,22H,2-3,5-6,8-11,14-15H2,1H3,(H,23,24)/b7-4-,13-12+/t16-,17+,18+,19?,20-/m1/s1
PubChem CID	44311013
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50018531
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
193624	Prostacyclin receptor	P43119	PTGIR	Homo sapiens (Human)	386
460931	Prostaglandin E2 receptor EP1 subtype	P34995	PTGER1	Homo sapiens (Human)	402
193623	Prostaglandin E2 receptor EP2 subtype	P43116	PTGER2	Homo sapiens (Human)	358
460933	Prostaglandin E2 receptor EP3 subtype	P43115	PTGER3	Homo sapiens (Human)	390
460934	Prostaglandin E2 receptor EP4 subtype	P35408	PTGER4	Homo sapiens (Human)	488
193622	Prostaglandin F2-alpha receptor	P43088	PTGFR	Homo sapiens (Human)	359
193625	Prostaglandin F2-alpha receptor	P43117	Ptgfr	Mus musculus (Mouse)	366
193626	Prostaglandin F2-alpha receptor	P37289	PTGFR	Bos taurus (Bovine)	362
460932	Thromboxane A2 receptor	P21731	TBXA2R	Homo sapiens (Human)	343

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