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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL185559
Molecular formula	C23H29F3O6
IUPAC name	(Z)-8-[(2R,3S,4R)-4-hydroxy-2-[(E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-enyl]oxolan-3-yl]oct-4-enoic acid
Molecular weight	458.474
Hydrogen bond acceptor	9
Hydrogen bond donor	3
XlogP	3.4
Synonyms	BDBM50150892 (Z)-8-{(2R,3S,4R)-4-Hydroxy-2-[(E)-(R)-3-hydroxy-4-(3-trifluoromethyl-phenoxy)-but-1-enyl]-tetrahydro-furan-3-yl}-oct-4-enoic acid
Inchi Key	YSNMVDVQOSTSDX-YCDPIYLCSA-N
Inchi ID	InChI=1S/C23H29F3O6/c24-23(25,26)16-7-6-8-18(13-16)31-14-17(27)11-12-21-19(20(28)15-32-21)9-4-2-1-3-5-10-22(29)30/h1,3,6-8,11-13,17,19-21,27-28H,2,4-5,9-10,14-15H2,(H,29,30)/b3-1-,12-11+/t17-,19+,20+,21-/m1/s1
PubChem CID	44393431
ChEMBL	CHEMBL185559
IUPHAR	N/A
BindingDB	50150892
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
418202	Prostaglandin F2-alpha receptor	P37289	PTGFR	Bos taurus (Bovine)	362
418203	Prostaglandin F2-alpha receptor	P43088	PTGFR	Homo sapiens (Human)	359

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