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| Name | Lutropin-choriogonadotropic hormone receptor |
|---|---|
| Species | Homo sapiens (Human) |
| Gene | LHCGR |
| Synonym | lutropin-choriogonadotropic hormone receptor Luteinizing hormone receptor LSH-R LHR LH/CG-R [ Show all ] |
| Disease | Heart disease Breast cancer Cancer Myelodysplastic syndrome Female infertility [ Show all ] |
| Length | 699 |
| Amino acid sequence | MKQRFSALQLLKLLLLLQPPLPRALREALCPEPCNCVPDGALRCPGPTAGLTRLSLAYLPVKVIPSQAFRGLNEVIKIEISQIDSLERIEANAFDNLLNLSEILIQNTKNLRYIEPGAFINLPRLKYLSICNTGIRKFPDVTKVFSSESNFILEICDNLHITTIPGNAFQGMNNESVTLKLYGNGFEEVQSHAFNGTTLTSLELKENVHLEKMHNGAFRGATGPKTLDISSTKLQALPSYGLESIQRLIATSSYSLKKLPSRETFVNLLEATLTYPSHCCAFRNLPTKEQNFSHSISENFSKQCESTVRKVNNKTLYSSMLAESELSGWDYEYGFCLPKTPRCAPEPDAFNPCEDIMGYDFLRVLIWLINILAIMGNMTVLFVLLTSRYKLTVPRFLMCNLSFADFCMGLYLLLIASVDSQTKGQYYNHAIDWQTGSGCSTAGFFTVFASELSVYTLTVITLERWHTITYAIHLDQKLRLRHAILIMLGGWLFSSLIAMLPLVGVSNYMKVSICFPMDVETTLSQVYILTILILNVVAFFIICACYIKIYFAVRNPELMATNKDTKIAKKMAILIFTDFTCMAPISFFAISAAFKVPLITVTNSKVLLVLFYPINSCANPFLYAIFTKTFQRDFFLLLSKFGCCKRRAELYRRKDFSAYTSNCKNGFTGSNKPSQSTLKLSTLHCQGTALLDKTRYTEC |
| UniProt | P22888 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | T79473 |
| ChEMBL | CHEMBL1854 |
| IUPHAR | N/A |
| DrugBank | BE0000134 |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 3713 |  AC1NW0NQ | C14H13NO4S | 291.321 | 5 / 0 | 2.5 | Yes |
| 4691 |  N-[4-(2,5-Dimethoxy-phenyl)-thiazol-2-yl]-N-ethyl-propionamide | C16H20N2O3S | 320.407 | 5 / 0 | 3.1 | Yes |
| 7540 |  SMR000204386 | C12H13NO5 | 251.238 | 5 / 0 | 2.4 | Yes |
| 9515 |  CHEMBL209634 | C23H22N4O2S2 | 450.575 | 7 / 2 | 5.5 | No |
| 12982 |  CHEMBL448753 | C18H19NO2 | 281.355 | 2 / 1 | 4.4 | Yes |
| 15609 |  MLS001007754 | C18H16N4O2S | 352.412 | 4 / 3 | 2.7 | Yes |
| 15834 |  (1Z,3Z)-1,4-bis(butylsulfonyl)buta-1,3-diene | C12H22O4S2 | 294.424 | 4 / 0 | 2.1 | Yes |
| 16522 |  2-(2-fluoro[1,1'-biphenyl]-4-yl)-N-(4-methylphenyl)propanamide | C22H20FNO | 333.406 | 2 / 1 | 5.8 | No |
| 16695 |  MLS000417923 | C24H22N4O2S | 430.526 | 5 / 1 | 3.9 | Yes |
| 17395 |  SMR000241362 | C24H24N2O6S | 468.524 | 7 / 1 | 3.5 | Yes |
| 18536 |  MLS000550953 | C24H27N3O6S2 | 517.615 | 9 / 1 | N/A | No |
| 18611 |  AC1LRXHJ | C24H29F3N2O3 | 450.502 | 6 / 1 | 5.9 | No |
| 18979 |  CHEMBL475564 | C24H21Cl2NO2 | 426.337 | 2 / 1 | 7.3 | No |
| 23261 |  MLS000535841 | C21H15ClN2O3S2 | 442.932 | 6 / 1 | 5.6 | No |
| 26402 |  goserelin | C59H84N18O14 | 1269.43 | 16 / 17 | -1.5 | No |
| 29869 |  7-chloro-N-methyl-4-nitro-2,1,3-benzoxadiazol-5-amine | C7H5ClN4O3 | 228.592 | 6 / 1 | 2.2 | Yes |
| 30586 |  MLS001116397 | C20H19ClN4O5S2 | 494.965 | 8 / 1 | 2.6 | Yes |
| 31135 |  SMR000236991 | C22H18N2O3S2 | 422.517 | 5 / 1 | 4.3 | Yes |
| 31240 |  MLS000850078 | C20H21NO5S | 387.45 | 6 / 2 | 4.6 | Yes |
| 35802 |  CHEMBL492929 | C25H19NO2 | 365.432 | 2 / 1 | 6.3 | No |
| 40903 |  AC1M9SY4 | C19H15Cl2N3O3S | 436.307 | 5 / 2 | 3.4 | Yes |
| 41022 |  CHEMBL397316 | C32H37N5O3 | 539.68 | 5 / 3 | 5.0 | No |
| 41404 |  184763-55-1 | C14H14ClN3O4 | 323.733 | 7 / 1 | N/A | N/A |
| 41459 |  CHEMBL509622 | C24H22ClNO2 | 391.895 | 2 / 1 | 6.7 | No |
| 41791 |  MLS000390934 | C23H20N4O2S | 416.499 | 5 / 1 | 3.5 | Yes |
| 43401 |  MLS000109200 | C21H24N2O6S | 432.491 | 7 / 1 | 2.1 | Yes |
| 45487 |  CHEMBL246321 | C32H37N5O3 | 539.68 | 5 / 3 | 5.0 | No |
| 46173 |  CHEMBL211871 | C19H21N3O3S2 | 403.515 | 8 / 1 | 5.1 | No |
| 46741 |  MLS000700440 | C15H10Cl2N4O2 | 349.171 | 5 / 0 | 3.5 | Yes |
| 47033 |  GNF-Pf-2335 | C26H33ClN2O2 | 441.012 | 3 / 0 | N/A | N/A |
| 49885 |  3,5-diphenylphenol | C18H14O | 246.309 | 1 / 1 | 4.8 | Yes |
| 52728 |  MLS002181440 | C25H30N2O3 | 406.526 | 4 / 0 | 5.3 | No |
| 52883 |  methylene blue | C16H18ClN3S | 319.851 | 4 / 0 | N/A | N/A |
| 54796 |  MLS001177315 | C25H26N2O4 | 418.493 | 4 / 1 | 3.8 | Yes |
| 57385 |  CHEMBL1651828 | C29H38N12O4S2 | 682.823 | 14 / 4 | 3.7 | No |
| 57868 |  MLS000041320 | C22H23N5 | 357.461 | 4 / 1 | 3.9 | Yes |
| 59131 |  Fertirelin | C55H76N16O12 | 1153.31 | 14 / 15 | -1.0 | No |
| 63973 |  CHEMBL377399 | C20H24N4O2S2 | 416.558 | 7 / 1 | 4.7 | Yes |
| 64185 |  MLS001005680 | C29H25ClN2 | 436.983 | 2 / 0 | N/A | N/A |
| 64557 |  CHEMBL211129 | C19H21FN4O2S2 | 420.521 | 8 / 2 | 4.6 | Yes |
| 65008 |  MLS000374746 | C20H18Cl2N4O4S | 481.348 | 6 / 0 | 2.5 | Yes |
| 66931 |  2,3-dichloro-5,8-dimethoxy-1,4-naphthoquinone | C12H8Cl2O4 | 287.092 | 4 / 0 | 3.1 | Yes |
| 70180 |  Org41841 | C19H22N4O2S2 | 402.531 | 7 / 2 | 4.5 | Yes |
| 74198 |  CHEMBL429108 | C31H36N4O2 | 496.655 | 4 / 2 | 6.0 | No |
| 74856 |  MLS000675932 | C16H12ClN3O3S | 361.8 | 5 / 1 | 2.8 | Yes |
| 79403 |  4-chloro-1-ethyl-3-nitroquinolin-2(1H)-one | C11H9ClN2O3 | 252.654 | 3 / 0 | 2.3 | Yes |
| 83985 |  CHEMBL514036 | C22H21NO2 | 331.415 | 2 / 1 | 5.6 | No |
| 84508 |  MLS000861241 | C15H18N4O3S | 334.394 | 6 / 0 | 3.4 | Yes |
| 85474 |  CHEMBL211872 | C17H18N4O2S2 | 374.477 | 7 / 2 | 3.9 | Yes |
| 85895 |  SMR000119525 | C22H25F3N2O3 | 422.448 | 6 / 1 | 4.7 | Yes |
| 86838 |  MLS000537855 | C16H13F5N2O2 | 360.284 | 7 / 2 | 4.7 | Yes |
| 89235 |  CHEMBL475454 | C25H25NO3 | 387.479 | 3 / 1 | 6.0 | No |
| 92252 |  1-[2-(4-fluorophenyl)ethyl]-3-(4-nitrophenyl)thiourea | C15H14FN3O2S | 319.354 | 4 / 2 | 3.4 | Yes |
| 95538 |  CHEMBL442831 | C26H27NO4 | 417.505 | 4 / 1 | 6.0 | No |
| 103411 |  GNF-PF-2893 | C16H19N3O3S | 333.406 | 4 / 2 | 3.2 | Yes |
| 103689 |  CHEMBL439392 | C33H40N6O3 | 568.722 | 6 / 4 | 5.4 | No |
| 104536 |  CHEMBL516048 | C23H23NO2 | 345.442 | 2 / 1 | 5.7 | No |
| 104827 |  SMR000154886 | C21H20N2O2 | 332.403 | 4 / 1 | 5.0 | Yes |
| 106149 |  MLS001116367 | C19H17ClN4O5S2 | 480.938 | 8 / 1 | 2.3 | Yes |
| 109640 |  MLS000070402 | C24H29N5O5S | 499.586 | 8 / 3 | 3.6 | Yes |
| 110943 |  MLS000078398 | C22H20FN5O2 | 405.433 | 7 / 1 | 3.4 | Yes |
| 111092 |  SMR000195611 | C24H22N2O5S | 450.509 | 7 / 2 | 4.1 | Yes |
| 113879 |  CHEMBL514154 | C22H21NO2 | 331.415 | 2 / 1 | 5.6 | No |
| 114503 |  AC1M4HAF | C19H19N3O4S | 385.438 | 6 / 2 | 3.4 | Yes |
| 117577 |  MLS000572338 | C17H11F6NO | 359.271 | 7 / 1 | 5.4 | No |
| 120489 |  MLS000393867 | C19H16ClFN4O5S2 | 498.928 | 9 / 1 | 3.7 | Yes |
| 121919 |  CHEMBL1651822 | C67H76N14O8S2 | 1269.56 | 18 / 5 | 8.4 | No |
| 121921 |  CHEMBL1651825 | C67H76N14O8S2 | 1269.56 | 18 / 5 | 8.4 | No |
| 123042 |  CHEMBL213681 | C17H17N3O3S2 | 375.461 | 8 / 1 | 4.5 | Yes |
| 126170 |  MLS001157505 | C24H30ClN5O3S2 | 536.106 | 8 / 1 | 4.6 | No |
| 126624 |  CHEMBL475453 | C24H19Cl4NO2 | 495.221 | 2 / 1 | 8.5 | No |
| 129647 |  NSC228155 | C11H6N4O4S | 290.253 | 7 / 0 | 1.3 | Yes |
| 134244 |  MLS001116146 | C20H18ClN3O5S | 447.89 | 7 / 1 | 3.0 | Yes |
| 137219 |  MLS000584447 | C15H16N6O5S | 392.39 | 10 / 1 | 2.4 | Yes |
| 139093 |  CHEMBL473647 | C21H19NO2 | 317.388 | 2 / 1 | 5.1 | No |
| 140523 |  BRD-A72341983-001-05-8 | C19H23ClN4O5S2 | 486.986 | 8 / 1 | 2.5 | Yes |
| 144991 |  MLS000417430 | C20H18ClN3O4S | 431.891 | 5 / 3 | 3.4 | Yes |
| 146170 |  SMR000065521 | C17H16N2O4S2 | 376.445 | 7 / 1 | 3.4 | Yes |
| 147913 |  SCHEMBL11803644 | C21H23IN2 | 430.333 | 2 / 0 | N/A | N/A |
| 148167 |  MLS001066072 | C30H26F3N3O4 | 549.55 | 9 / 2 | N/A | No |
| 149665 |  SMR000176548 | C22H15N3O3 | 369.38 | 6 / 0 | 3.8 | Yes |
| 155976 |  Quinaldine red | C21H23IN2 | 430.333 | 2 / 0 | N/A | N/A |
| 157159 |  MLS000394125 | C22H25N3O5S | 443.518 | 6 / 1 | 2.5 | Yes |
| 157732 |  MLS000516165 | C21H18N4O3S | 406.46 | 6 / 1 | 2.9 | Yes |
| 159688 |  3,5-dimethyl-4-[(4-nitrophenyl)thio]-1-(phenylsulfonyl)-1H-pyrazole | C17H15N3O4S2 | 389.444 | 6 / 0 | 4.2 | Yes |
| 162690 |  SMR000016535 | C21H17N3O3S | 391.445 | 5 / 1 | 4.8 | Yes |
| 165773 |  AC1M4K3J | C23H28N2O3S | 412.548 | 5 / 0 | 4.3 | Yes |
| 167409 |  CHEMBL247945 | C38H35N5O3 | 609.73 | 5 / 3 | 7.0 | No |
| 168320 |  CHEMBL245663 | C32H37N5O3 | 539.68 | 5 / 3 | 5.0 | No |
| 168660 |  MLS000706839 | C16H13Cl3N2O3S | 419.701 | 5 / 1 | 3.6 | Yes |
| 169190 |  CHEMBL269261 | C36H46N6O3 | 610.803 | 6 / 3 | 6.3 | No |
| 171448 |  MLS000757112 | C12H12Cl2N2O4 | 319.138 | 4 / 2 | 1.4 | Yes |
| 172742 |  SMR000131285 | C23H20ClN3O2S | 437.942 | 5 / 2 | 5.6 | No |
| 173904 |  CHEMBL247700 | C32H38N6O3 | 554.695 | 6 / 4 | 5.1 | No |
| 174268 |  CHEMBL378091 | C18H20N4O2S2 | 388.504 | 7 / 3 | 4.2 | Yes |
| 174622 |  79966-13-5 | C10H7ClN2O3 | 238.627 | 3 / 0 | 1.9 | Yes |
| 177956 |  MLS000689048 | C25H27N5O4S | 493.582 | 7 / 0 | N/A | N/A |
| 181276 |  CHEMBL209214 | C17H18N4O3S2 | 390.476 | 8 / 3 | 2.8 | Yes |
| 182556 |  MLS001182319 | C12H13N7O2S2 | 351.403 | 8 / 0 | 2.1 | Yes |
| 185307 |  AC1LJT2A | C24H24N4O3S | 448.541 | 5 / 2 | 4.3 | Yes |
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