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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SMR000016535
Molecular formula	C21H17N3O3S
IUPAC name	N-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-methyl-6-phenylimidazo[2,1-b][1,3]thiazole-2-carboxamide
Molecular weight	391.445
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	4.8
Synonyms	AC1MMIRH MolPort-000-478-475 ZINC4004675 CHEMBL1597278 N-(2H,3H-benzo[3,4-e]1,4-dioxin-6-yl)(3-methyl-6-phenylimidazo[2,1-b]1,3-thiaz olin-2-yl)carboxamide MLS000089447 SR-01000130393-1 AKOS001834660 N-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-methyl-6-phenylimidazo[2,1-b][1,3]thiazole-2-carboxamide F0650-0089 852133-64-3 MLS000102089 ST50115384 N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-3-methyl-6-phenylimidazo[2,1-b]thiazole-2-carboxamide HMS2475J16 SR-01000130393 [ Show all ]
Inchi Key	JXUCHAKTXGLSLB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H17N3O3S/c1-13-19(20(25)22-15-7-8-17-18(11-15)27-10-9-26-17)28-21-23-16(12-24(13)21)14-5-3-2-4-6-14/h2-8,11-12H,9-10H2,1H3,(H,22,25)
PubChem CID	3239406
ChEMBL	CHEMBL1597278
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
162689	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
162690	Lutropin-choriogonadotropic hormone receptor	P22888	LHCGR	Homo sapiens (Human)	699
162691	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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