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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000070402
Molecular formula	C24H29N5O5S
IUPAC name	4-amino-5-N-(2-ethoxyphenyl)-5-N-[1-(furan-2-yl)-2-(3-methylbutylamino)-2-oxoethyl]-1,2-thiazole-3,5-dicarboxamide
Molecular weight	499.586
Hydrogen bond acceptor	8
Hydrogen bond donor	3
XlogP	3.6
Synonyms	4-Amino-isothiazole-3,5-dicarboxylic acid 3-amide 5-{(2-ethoxy-phenyl)-[furan-2-yl-(3-methyl-butylcarbamoyl)-methyl]-amide} BDBM44573 4-azanyl-N5-(2-ethoxyphenyl)-N5-[1-(furan-2-yl)-2-(3-methylbutylamino)-2-oxidanylidene-ethyl]-1,2-thiazole-3,5-dicarboxamide cid_652855 AKOS030476198 MLS000880152 4-amino-N''-[1-(2-furyl)-2-(isoamylamino)-2-keto-ethyl]-N''-o-phenetyl-isothiazole-3,5-dicarboxamide AC1LCN4T HMS2467F23 4-amino-5-N-(2-ethoxyphenyl)-5-N-[1-(furan-2-yl)-2-(3-methylbutylamino)-2-oxoethyl]-1,2-thiazole-3,5-dicarboxamide ASN 03873587 SMR000002697 4-amino-N5-(2-ethoxyphenyl)-N5-[1-(2-furanyl)-2-(3-methylbutylamino)-2-oxoethyl]isothiazole-3,5-dicarboxamide CHEMBL1332051 AKOS000793486 [ Show all ]
Inchi Key	GZZFUMZXCCWZTC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H29N5O5S/c1-4-33-16-9-6-5-8-15(16)29(24(32)21-18(25)19(22(26)30)28-35-21)20(17-10-7-13-34-17)23(31)27-12-11-14(2)3/h5-10,13-14,20H,4,11-12,25H2,1-3H3,(H2,26,30)(H,27,31)
PubChem CID	652855
ChEMBL	CHEMBL1332051
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
109639	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
109640	Lutropin-choriogonadotropic hormone receptor	P22888	LHCGR	Homo sapiens (Human)	699
109638	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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