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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000535841
Molecular formula	C21H15ClN2O3S2
IUPAC name	(NE)-N-[3-(5-chloro-2-methylanilino)-4-oxonaphthalen-1-ylidene]thiophene-2-sulfonamide
Molecular weight	442.932
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	5.6
Synonyms	(NE)-N-[3-(5-chloro-2-methylanilino)-4-oxo-1-naphthalenylidene]-2-thiophenesulfonamide HMS3091O05 BDBM41036 SMR000151319 cid_11834461 (NE)-N-[3-(5-chloro-2-methylanilino)-4-oxonaphthalen-1-ylidene]thiophene-2-sulfonamide SMR001544598 (NE)-N-[3-(5-chloro-2-methyl-anilino)-4-keto-1-naphthylidene]thiophene-2-sulfonamide HMS2400G07 (NE)-N-[3-[(5-chloranyl-2-methyl-phenyl)amino]-4-oxidanylidene-naphthalen-1-ylidene]thiophene-2-sulfonamide MLS002636663 CHEMBL2006503 [ Show all ]
Inchi Key	BGOWMRGDUSUEFJ-HKOYGPOVSA-N
Inchi ID	InChI=1S/C21H15ClN2O3S2/c1-13-8-9-14(22)11-17(13)23-19-12-18(15-5-2-3-6-16(15)21(19)25)24-29(26,27)20-7-4-10-28-20/h2-12,23H,1H3/b24-18+
PubChem CID	11834461
ChEMBL	CHEMBL2006503
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
23261	Lutropin-choriogonadotropic hormone receptor	P22888	LHCGR	Homo sapiens (Human)	699
23260	Neuropeptide S receptor	Q6W5P4	NPSR1	Homo sapiens (Human)	371
465765	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593
23259	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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