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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL377399
Molecular formula	C20H24N4O2S2
IUPAC name	5-amino-N-tert-butyl-4-(3-methoxyphenyl)-N-methyl-2-methylsulfanylthieno[2,3-d]pyrimidine-6-carboxamide
Molecular weight	416.558
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	4.7
Synonyms	BDBM50189779 N-tert-butyl-5-amino-4-(3-methoxyphenyl)-N-methyl-2-(methylthio)thieno[2,3-d]pyrimidine-6-carboxamide SCHEMBL4319786
Inchi Key	DMRRHPRFHJRTBN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H24N4O2S2/c1-20(2,3)24(4)18(25)16-14(21)13-15(11-8-7-9-12(10-11)26-5)22-19(27-6)23-17(13)28-16/h7-10H,21H2,1-6H3
PubChem CID	11654606
ChEMBL	CHEMBL377399
IUPHAR	N/A
BindingDB	50189779
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
63973	Lutropin-choriogonadotropic hormone receptor	P22888	LHCGR	Homo sapiens (Human)	699
63972	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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