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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS001157505
Molecular formula	C24H30ClN5O3S2
IUPAC name	N-[4-chloro-3-(diethylsulfamoyl)phenyl]-1-(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
Molecular weight	536.106
Hydrogen bond acceptor	8
Hydrogen bond donor	1
XlogP	4.6
Synonyms	AKOS008037890 ZINC38140490 HMS3034J19 MolPort-005-728-724 MCULE-9370284749 SMR000708984 CHEMBL1456022 [ Show all ]
Inchi Key	HXFRQMAAIGNPOJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H30ClN5O3S2/c1-5-30(6-2)35(32,33)20-13-18(7-8-19(20)25)28-23(31)17-9-11-29(12-10-17)22-21-15(3)16(4)34-24(21)27-14-26-22/h7-8,13-14,17H,5-6,9-12H2,1-4H3,(H,28,31)
PubChem CID	24981282
ChEMBL	CHEMBL1456022
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
126172	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
126170	Lutropin-choriogonadotropic hormone receptor	P22888	LHCGR	Homo sapiens (Human)	699
126171	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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