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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	goserelin
Molecular formula	C59H84N18O14
IUPAC name	(2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-[(2S)-2-[(carbamoylamino)carbamoyl]pyrrolidin-1-yl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-[(2-methylpropan-2-yl)oxy]-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
Molecular weight	1269.43
Hydrogen bond acceptor	16
Hydrogen bond donor	17
XlogP	-1.5
Synonyms	1-(5-Oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-O-tert-butyl-D-seryl-L-leucyl-L-arginyl-L-prolyl)semicarbazide 81G926 D04405 Goserelin (USAN/INN) Goserelinum ICI 118630 SCHEMBL8643 6-[O-(1,1-Dimethylethyl)-D-serine]-1-9-luteinizing Hormone-releasing Factor (swine) 2-(Aminocarbonyl)hydrazide Acetate AKOS015994653 D-Ser(But)6Azgly10-gonadorelin Decapeptide I Goserelin [USAN:INN:BAN] HMS2089D16 Luteinizing hormone-releasing factor (pig), 6-(O-(1,1-dimethylethyl)-D-serine)-10-deglycinamide-, 2-(aminocarbonyl)hydrazide Zoladex 70280-59-0 B3723 D-Ser(t-Bu)(sup 6)aza-gly(sup 10)-GNRH Fertilan Deuterated Gosereline HY-13673 SCHEMBL19712239 145781-92-6 AB01275466-01 CHEMBL1201247 Goserelin acetate Goserelinum [Latin] ICI-118630 UNII-0F65R8P09N 6-[O-(1,1-Dimethylethyl)-D-serine]-1-9-luteinizing Hormone-releasing Factor (swine) 2-(Aminocarbonyl)hydrazide Acetate Deuterated AKOS030213245 D-Ser(But)6Azgly10-gonadorelin Deuterated DTXSID7048297 Goserelina HS-2015 MFCD01747329 Zoladex (TN) 0F65R8P09N 807G025 CHEBI:5523 D00BCG Gosereline [French] ICI 118,630 SCHEMBL20459194 4-D-Ser-goserelin AC1NSK1T CS-3114 DB00014 Goserelin Deuterated Acetate GTPL3879 KS-00002WUS ZD-9393 65807-02-5 AstraZeneca (TN) D-Ser(But)6Azgly10LHRH Fertilan Goserelina [Spanish] HSDB 7606 MolPort-006-823-831 [D-Ser(tBu)6,Azagly10]-LHRH acetate salt [ Show all ]
Inchi Key	BLCLNMBMMGCOAS-URPVMXJPSA-N
Inchi ID	InChI=1S/C59H84N18O14/c1-31(2)22-40(49(82)68-39(12-8-20-64-57(60)61)56(89)77-21-9-13-46(77)55(88)75-76-58(62)90)69-54(87)45(29-91-59(3,4)5)74-50(83)41(23-32-14-16-35(79)17-15-32)70-53(86)44(28-78)73-51(84)42(24-33-26-65-37-11-7-6-10-36(33)37)71-52(85)43(25-34-27-63-30-66-34)72-48(81)38-18-19-47(80)67-38/h6-7,10-11,14-17,26-27,30-31,38-46,65,78-79H,8-9,12-13,18-25,28-29H2,1-5H3,(H,63,66)(H,67,80)(H,68,82)(H,69,87)(H,70,86)(H,71,85)(H,72,81)(H,73,84)(H,74,83)(H,75,88)(H4,60,61,64)(H3,62,76,90)/t38-,39-,40-,41-,42-,43-,44-,45+,46-/m0/s1
PubChem CID	5311128
ChEMBL	CHEMBL1201247
IUPHAR	N/A
BindingDB	N/A
DrugBank	DB00014
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor. This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
26403	Gonadotropin-releasing hormone receptor	P30968	GNRHR	Homo sapiens (Human)	328
26402	Lutropin-choriogonadotropic hormone receptor	P22888	LHCGR	Homo sapiens (Human)	699

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