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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000394125
Molecular formula	C22H25N3O5S
IUPAC name	2-butyl-N-[3-(dimethylsulfamoyl)-4-methylphenyl]-1,3-dioxoisoindole-5-carboxamide
Molecular weight	443.518
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	2.5
Synonyms	MCULE-6980001265 AB00542596-02 SMR000247719 CHEMBL1462123 2-butyl-N-[3-(dimethylsulfamoyl)-4-methylphenyl]-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxamide AKOS000920146 Z26500160 HMS2511F03 919916-24-8 MolPort-003-199-007 ZINC8692861 [ Show all ]
Inchi Key	JQECRWINANQWRS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H25N3O5S/c1-5-6-11-25-21(27)17-10-8-15(12-18(17)22(25)28)20(26)23-16-9-7-14(2)19(13-16)31(29,30)24(3)4/h7-10,12-13H,5-6,11H2,1-4H3,(H,23,26)
PubChem CID	15945376
ChEMBL	CHEMBL1462123
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
157160	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
157159	Lutropin-choriogonadotropic hormone receptor	P22888	LHCGR	Homo sapiens (Human)	699
482340	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593
157161	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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