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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS001116367
Molecular formula	C19H17ClN4O5S2
IUPAC name	5-chloro-N-[4-[methyl(phenyl)sulfamoyl]phenyl]-2-methylsulfonylpyrimidine-4-carboxamide
Molecular weight	480.938
Hydrogen bond acceptor	8
Hydrogen bond donor	1
XlogP	2.3
Synonyms	HMS1843D06 ZINC8611924 5-chloro-2-mesyl-N-[4-[methyl(phenyl)sulfamoyl]phenyl]pyrimidine-4-carboxamide CCG-100325 MLS003880622 5-chloro-N-[4-[methyl(phenyl)sulfamoyl]phenyl]-2-methylsulfonylpyrimidine-4-carboxamide cid_16012865 SMR000625581 AKOS001873227 MCULE-9344992102 5-chloro-N-(4-{[methyl(phenyl)amino]sulfonyl}phenyl)-2-(methylsulfonyl)pyrimidine-4-carboxamide MolPort-000-399-296 5-chloro-N-{4-[methyl(phenyl)sulfamoyl]phenyl}-2-(methylsulfonyl)pyrimidine-4-carboxamide D053-0282 STK908420 5-chloranyl-N-[4-[methyl(phenyl)sulfamoyl]phenyl]-2-methylsulfonyl-pyrimidine-4-carboxamide BDBM67354 5-chloro-N-[4-[methyl(phenyl)sulfamoyl]phenyl]-2-methylsulfonyl-4-pyrimidinecarboxamide CHEMBL1332454 NCGC00115040-01 [ Show all ]
Inchi Key	GVDDPQRQWABRJN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H17ClN4O5S2/c1-24(14-6-4-3-5-7-14)31(28,29)15-10-8-13(9-11-15)22-18(25)17-16(20)12-21-19(23-17)30(2,26)27/h3-12H,1-2H3,(H,22,25)
PubChem CID	16012865
ChEMBL	CHEMBL1332454
IUPHAR	N/A
BindingDB	67354
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
106152	Apelin receptor	P35414	APLNR	Homo sapiens (Human)	380
106148	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
106149	Lutropin-choriogonadotropic hormone receptor	P22888	LHCGR	Homo sapiens (Human)	699
476000	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593
106150	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764
106151	Type-1 angiotensin II receptor	P30556	AGTR1	Homo sapiens (Human)	359

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