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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL378091
Molecular formula	C18H20N4O2S2
IUPAC name	5-amino-N-tert-butyl-4-(3-hydroxyphenyl)-2-methylsulfanylthieno[2,3-d]pyrimidine-6-carboxamide
Molecular weight	388.504
Hydrogen bond acceptor	7
Hydrogen bond donor	3
XlogP	4.2
Synonyms	SCHEMBL4315364 BDBM50189774 KORCEMCZKYMFIO-UHFFFAOYSA-N tert-Butyl 5-amino-2-methylthio-4-(3-hydroxyphenyl)-thieno[2,3-d]pyrimidine-6-carboxamide N-tert-butyl-5-amino-4-(3-hydroxyphenyl)-2-(methylthio)thieno[2,3-d]pyrimidine-6-carboxamide
Inchi Key	KORCEMCZKYMFIO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H20N4O2S2/c1-18(2,3)22-15(24)14-12(19)11-13(9-6-5-7-10(23)8-9)20-17(25-4)21-16(11)26-14/h5-8,23H,19H2,1-4H3,(H,22,24)
PubChem CID	11531195
ChEMBL	CHEMBL378091
IUPHAR	N/A
BindingDB	50189774
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
174268	Lutropin-choriogonadotropic hormone receptor	P22888	LHCGR	Homo sapiens (Human)	699
174269	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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