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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SB-258510
Molecular formula	C21H24ClN3O3S2
IUPAC name	5-chloro-N-[4-methoxy-3-(4-methylpiperazin-1-yl)phenyl]-3-methyl-1-benzothiophene-2-sulfonamide
Molecular weight	466.011
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	4.7
Synonyms	SCHEMBL1136525 5-chloro-3-methyl-benzo[b]thiophene-2-sulphonic acid[4-methoxy-3-(4-methyl-piperazin-1-yl)phenyl]amide PDSP2_001356 AC1OCFOR ZINLARKOVIPOJW-UHFFFAOYSA-N 5-Chloro-3-methyl-benzo[b]thiophene-2-sulfonic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-amide CHEMBL29846 5-chloro-N-[4-methoxy-3-(4-methylpiperazin-1-yl)phenyl]-3-methyl-1-benzothiophene-2-sulfonamide BDBM50130286 5-chloro-3-methyl-benzo[b]thiophene-2-sulphonic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)phenyl]amide PDSP1_001372 [ Show all ]
Inchi Key	ZINLARKOVIPOJW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H24ClN3O3S2/c1-14-17-12-15(22)4-7-20(17)29-21(14)30(26,27)23-16-5-6-19(28-3)18(13-16)25-10-8-24(2)9-11-25/h4-7,12-13,23H,8-11H2,1-3H3
PubChem CID	6918648
ChEMBL	CHEMBL29846
IUPHAR	N/A
BindingDB	50130286
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
429385	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
429394	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
429383	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
429387	5-hydroxytryptamine receptor 1E	P28566	HTR1E	Homo sapiens (Human)	365
429393	5-hydroxytryptamine receptor 1F	P30939	HTR1F	Homo sapiens (Human)	366
429382	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
429390	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
429384	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
429392	5-hydroxytryptamine receptor 4	Q13639	HTR4	Homo sapiens (Human)	388
429380	5-hydroxytryptamine receptor 6	Q9R1C8	Htr6	Mus musculus (Mouse)	440
429391	5-hydroxytryptamine receptor 6	P50406	HTR6	Homo sapiens (Human)	440
429395	5-hydroxytryptamine receptor 6	P31388	Htr6	Rattus norvegicus (Rat)	436
429388	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479
429381	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
429389	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
429386	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400

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