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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL263700
Molecular formula	C19H20N2O2
IUPAC name	[3-[2-(dimethylamino)ethyl]-5-hydroxyindol-1-yl]-phenylmethanone
Molecular weight	308.381
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	3.5
Synonyms	N,N-Dimethyl-1-benzoyl-5-hydroxy-1H-indole-3-ethanamine [3-(2-Dimethylamino-ethyl)-5-hydroxy-1H-indol-1-yl]phenylmethanone SCHEMBL7443507 [3-(2-Dimethylamino-ethyl)-5-hydroxy-indol-1-yl]-phenyl-methanone UJELDYRUBKQNKE-UHFFFAOYSA-N BDBM50106252 [ Show all ]
Inchi Key	UJELDYRUBKQNKE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H20N2O2/c1-20(2)11-10-15-13-21(18-9-8-16(22)12-17(15)18)19(23)14-6-4-3-5-7-14/h3-9,12-13,22H,10-11H2,1-2H3
PubChem CID	9796627
ChEMBL	CHEMBL263700
IUPHAR	N/A
BindingDB	50106252
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
338099	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
338094	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
338102	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
338103	5-hydroxytryptamine receptor 1F	P30939	HTR1F	Homo sapiens (Human)	366
338096	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
338101	5-hydroxytryptamine receptor 5A	P35364	Htr5a	Rattus norvegicus (Rat)	357
338097	5-hydroxytryptamine receptor 6	P50406	HTR6	Homo sapiens (Human)	440
338098	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479
338095	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
338100	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
338104	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467

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