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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	alprenolol
Molecular formula	C15H23NO2
IUPAC name	1-(propan-2-ylamino)-3-(2-prop-2-enylphenoxy)propan-2-ol
Molecular weight	249.354
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	3.1
Synonyms	AB00053431-13 Prestwick1_000250 allprenolol Spectrum2_001814 Alprenololum [INN-Latin] Yobir (TN) BPBio1_000044 DB00866 GTPL563 KBio2_003216 1-(2-Allylphenoxy)-3-isopropylamino-2-propanol MCULE-8135107027 13655-52-2 NCGC00015099-11 AC1Q57NL Regletin (TN) Alprenolol (INN) Spectrum5_001414 Aprenololo BSPBio_000040 CTK0H3293 DSSTox_GSID_45127 HMS2089G06 (-)-alprenolol hydrate d-tartrate KBioGR_001652 1-(o-Allylphenoxy)-3-isopropylamino)-2-propanol NCGC00015099-04 2-Propanol, 1-[(1-methylethyl)amino]-3-[2-(2-propenyl)phenoxy]- NCGC00089741-04 PAZJSJFMUHDSTF-UHFFFAOYSA-N Alfeprol SPBio_001827 ALPRENOLOL,(-) Tox21_110084_1 Atenenol CCG-204247 D07156 Duriles (TN) KBio1_000015 Lopac0_000152 1-[2-(propen-2-ylphenoxy)]-3-(isopropylamino)propan-2-ol NCGC00015099-08 655A522 AB00053431_14 Prestwick2_000250 Alpheprol Spectrum3_001066 API0006555 {2-hydroxy-3-[2-(prop-2-en-1-yl)phenoxy]propyl}(propan-2-yl)amine BRD-A00993607-003-05-5 CHEMBL266195 DivK1c_000015 Gubernal (TN) KBio2_005784 1-(isopropylamino)-3-(2-allylphenoxy)-2-propanol MolPort-003-717-938 2-Propanol, 1-((1-methylethyl)amino)-3-(2-(2-propenyl)phenoxy)- NCGC00089741-02 NINDS_000015 ACMC-1C1BC SBI-0050140.P003 Alprenolol [INN:BAN] Spectrum_000168 Aptine (TN) BSPBio_002652 d-isopropylamino-1(allyl 2'phenoxy)-3 propanol DSSTox_RID_80690 HY-B1517 (RS)-1-(2-allylphenoxy)-3-(isopropylamino)propan-2-ol KBioSS_000648 1-(propan-2-ylamino)-3-(2-prop-2-enylphenoxy)propan-2-ol NCGC00015099-05 Prestwick0_000250 Alfeprol [Russian] SPBio_002259 Alprenololum Yobir BDBM25764 CHEBI:51211 EINECS 237-140-9 KBio2_000648 1-(2-Allylphenoxy)-3-(isopropylamino)-2-propanol # LS-121647 122259-67-0 NCGC00015099-09 AB00053431 AC1L1CYO Prestwick3_000250 Spectrum4_001216 Apllobal (TN) BRD-A00993607-003-15-4 CS-5734 DSSTox_CID_25127 H-56-28 (-)-1-(o-Allylphenoxy)-3-(isopropylamino)-2-propanol KBio3_001872 1-(o-Allylphenoxy)-3-(isopropylamino)-2-propanol NCGC00015099-03 2-Propanol, 1-(o-allylphenoxy)-3-(isopropylamino)- NCGC00089741-03 Oprea1_368995 AKOS016376219 SCHEMBL34636 ALPRENOLOL,(+) Tox21_110084 Aptol (TN) CAS-13655-52-2 D01VAB DTXSID0045127 IDI1_000015 (RS)-Alprenolol;dl-Alprenolol L000961 1-isopropylamino-3-(2-allyl)phenoxypropan-2-ol NCGC00015099-06 [ Show all ]
Inchi Key	PAZJSJFMUHDSTF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C15H23NO2/c1-4-7-13-8-5-6-9-15(13)18-11-14(17)10-16-12(2)3/h4-6,8-9,12,14,16-17H,1,7,10-11H2,2-3H3
PubChem CID	2119
ChEMBL	CHEMBL266195
IUPHAR	563
BindingDB	25764
DrugBank	DB00866
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
255363	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
255366	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
255362	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
255364	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
556456	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
556454	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
255358	Beta-1 adrenergic receptor	P08588	ADRB1	Homo sapiens (Human)	477
255359	Beta-1 adrenergic receptor	P18090	Adrb1	Rattus norvegicus (Rat)	466
255357	Beta-2 adrenergic receptor	P07550	ADRB2	Homo sapiens (Human)	413
255365	Beta-2 adrenergic receptor	Q28044	ADRB2	Bos taurus (Bovine)	418
255367	Beta-2 adrenergic receptor	P10608	Adrb2	Rattus norvegicus (Rat)	418
255360	Beta-3 adrenergic receptor	P13945	ADRB3	Homo sapiens (Human)	408
255361	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
556455	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444

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