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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SB-214111
Molecular formula	C18H22BrN3O3S
IUPAC name	4-bromo-N-[4-methoxy-3-(4-methylpiperazin-1-yl)phenyl]benzenesulfonamide
Molecular weight	440.356
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	3.0
Synonyms	CHEMBL292759 4-bromo-N-[4-methoxy-3-(4-methylpiperazin-1-yl)phenyl]benzenesulfonamide PDSP1_001375 BDBM50073056 SCHEMBL6977519 209480-37-5 D05XGR PDSP2_001359 4-Bromo-N-[4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-benzenesulfonamide N-[3-(4-Methylpiperazino)-4-methoxyphenyl]-4-bromobenzenesulfonamide AC1OCFOP [ Show all ]
Inchi Key	OZYPUQNRUYTZDI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H22BrN3O3S/c1-21-9-11-22(12-10-21)17-13-15(5-8-18(17)25-2)20-26(23,24)16-6-3-14(19)4-7-16/h3-8,13,20H,9-12H2,1-2H3
PubChem CID	6918647
ChEMBL	CHEMBL292759
IUPHAR	N/A
BindingDB	50073056
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
254477	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
254482	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
254479	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
254475	5-hydroxytryptamine receptor 1E	P28566	HTR1E	Homo sapiens (Human)	365
254471	5-hydroxytryptamine receptor 1F	P30939	HTR1F	Homo sapiens (Human)	366
254480	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
254484	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
254474	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
254476	5-hydroxytryptamine receptor 4	Q13639	HTR4	Homo sapiens (Human)	388
254469	5-hydroxytryptamine receptor 6	P31388	Htr6	Rattus norvegicus (Rat)	436
254470	5-hydroxytryptamine receptor 6	P50406	HTR6	Homo sapiens (Human)	440
254472	5-hydroxytryptamine receptor 6	Q9R1C8	Htr6	Mus musculus (Mouse)	440
254483	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479
254473	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
254481	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
254478	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400

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