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Name | Chemokine-like receptor 1 |
---|---|
Species | Homo sapiens (Human) |
Gene | CMKLR1 |
Synonym | tazarotene induced gene 2 receptor RVER1 resolvin E1 receptor Gpcr27 G-protein coupled receptor DEZ [ Show all ] |
Disease | N/A |
Length | 373 |
Amino acid sequence | MRMEDEDYNTSISYGDEYPDYLDSIVVLEDLSPLEARVTRIFLVVVYSIVCFLGILGNGLVIIIATFKMKKTVNMVWFLNLAVADFLFNVFLPIHITYAAMDYHWVFGTAMCKISNFLLIHNMFTSVFLLTIISSDRCISVLLPVWSQNHRSVRLAYMACMVIWVLAFFLSSPSLVFRDTANLHGKISCFNNFSLSTPGSSSWPTHSQMDPVGYSRHMVVTVTRFLCGFLVPVLIITACYLTIVCKLQRNRLAKTKKPFKIIVTIIITFFLCWCPYHTLNLLELHHTAMPGSVFSLGLPLATALAIANSCMNPILYVFMGQDFKKFKVALFSRLVNALSEDTGHSSYPSHRSFTKMSSMNERTSMNERETGML |
UniProt | Q99788 |
Protein Data Bank | N/A |
GPCR-HGmod model | Q99788 |
3D structure model | This predicted structure model is from GPCR-EXP Q99788. |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL3540 |
IUPHAR | 79 |
DrugBank | N/A |
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GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
---|---|---|---|---|---|---|
535995 | CHEMBL3964891 | C28H29F8N3O2 | 591.546 | 11 / 1 | 5.9 | No |
535997 | CHEMBL3922201 | C28H29F8N3O2 | 591.546 | 11 / 1 | 5.9 | No |
536031 | CHEMBL3987046 | C21H18F6N2O2 | 444.377 | 8 / 1 | 4.3 | Yes |
536036 | CHEMBL3894891 | C29H33F6N3O2 | 569.592 | 9 / 1 | 6.0 | No |
536040 | CHEMBL3976686 | C25H26F6N2O3 | 516.484 | 9 / 2 | 4.7 | No |
536195 | CHEMBL3903711 | C24H26F3N3O3 | 461.485 | 7 / 1 | 3.2 | Yes |
536232 | SCHEMBL1603509 | C26H26F6N2O2 | 512.496 | 8 / 1 | 6.3 | No |
536251 | SCHEMBL8291491 | C23H22F6N2O2 | 472.431 | 8 / 1 | 5.3 | No |
536252 | CHEMBL3929292 | C23H22F6N2O2 | 472.431 | 8 / 1 | 5.3 | No |
553301 | 18S-Resolvin E1 | C20H30O5 | 350.455 | 5 / 4 | 2.4 | Yes |
553302 | Resolvin E1 | C20H30O5 | 350.455 | 5 / 4 | 2.4 | Yes |
536371 | CHEMBL3967594 | C23H20F6N2O2 | 470.415 | 8 / 1 | 4.9 | Yes |
536590 | CHEMBL3891997 | C26H31F3N2O3 | 476.54 | 6 / 1 | 5.5 | No |
536666 | SCHEMBL1602948 | C24H22F6N2O3 | 500.441 | 9 / 1 | 4.2 | No |
536682 | CHEMBL3986990 | C29H36F3N3O2 | 515.621 | 6 / 1 | 5.5 | No |
536699 | CHEMBL3894488 | C22H20F6N2O2 | 458.404 | 8 / 1 | 4.8 | Yes |
536841 | CHEMBL3890077 | C27H27F5N4O2 | 534.531 | 9 / 1 | 4.4 | No |
536876 | CHEMBL3943343 | C21H18F6N2O2 | 444.377 | 8 / 1 | 4.3 | Yes |
548298 | CHEMBL3911691 | C28H31F3N4O3 | 528.576 | 8 / 1 | 3.7 | No |
536947 | CHEMBL3895593 | C27H31F3N2O3 | 488.551 | 6 / 1 | 5.6 | No |
536966 | CHEMBL3949555 | C25H26F6N2O2 | 500.485 | 8 / 1 | 6.0 | No |
537037 | CHEMBL3971028 | C26H28F6N2O2 | 514.512 | 8 / 1 | 6.4 | No |
537038 | CHEMBL3983028 | C25H25F6N3O2 | 513.484 | 9 / 1 | 4.8 | No |
537082 | CHEMBL3913510 | C28H32F7N3O2 | 575.572 | 10 / 1 | 5.8 | No |
537107 | SCHEMBL1603112 | C25H26F6N2O2 | 500.485 | 8 / 1 | 5.8 | No |
537114 | CHEMBL3895675 | C25H27F3N2O2 | 444.498 | 5 / 1 | 5.1 | No |
537202 | SCHEMBL1604237 | C24H24F3N3O2 | 443.47 | 6 / 1 | 4.3 | Yes |
537395 | CHEMBL3951085 | C23H20F6N2O3 | 486.414 | 9 / 1 | 4.3 | Yes |
537483 | CHEMBL3933822 | C29H34F7N3O2 | 589.599 | 10 / 1 | 6.4 | No |
537501 | CHEMBL3971623 | C21H18F6N2O3 | 460.376 | 9 / 2 | 3.6 | Yes |
63638 | CHEMBL217053 | C18H13BrN2O4 | 401.216 | 5 / 1 | 3.5 | Yes |
537518 | SCHEMBL1604171 | C26H31F3N2O3 | 476.54 | 6 / 1 | 5.4 | No |
537523 | CHEMBL3967440 | C28H29F6N3O2 | 553.549 | 9 / 1 | 5.3 | No |
537599 | CHEMBL3934117 | C24H22F6N2O2 | 484.442 | 8 / 1 | 5.5 | No |
537646 | CHEMBL3891249 | C26H25F6N3O2 | 525.495 | 9 / 2 | 3.9 | No |
537672 | CHEMBL3986622 | C24H20F8N2O2 | 520.423 | 10 / 1 | 5.3 | No |
537707 | CHEMBL3892026 | C21H18F3N3O2 | 401.389 | 6 / 1 | 3.2 | Yes |
537737 | CHEMBL3951053 | C20H21ClN2O2 | 356.85 | 2 / 1 | 3.6 | Yes |
537857 | CHEMBL3954941 | C28H33F6N3O2 | 557.581 | 9 / 1 | 5.9 | No |
537876 | CHEMBL3941764 | C21H18F6N2O2 | 444.377 | 8 / 1 | 4.3 | Yes |
537910 | CHEMBL3961939 | C27H34F3N3O2 | 489.583 | 6 / 2 | 6.0 | No |
537920 | CHEMBL3976656 | C24H21F7N2O2 | 502.433 | 9 / 1 | 5.1 | No |
548808 | CHEMBL3934878 | C24H21F7N2O2 | 502.433 | 9 / 1 | 5.1 | No |
445126 | GSK137647A | C16H19NO3S | 305.392 | 4 / 1 | 3.5 | Yes |
538199 | CHEMBL3920550 | C22H19ClF6N2O2 | 492.846 | 8 / 1 | 5.4 | No |
538231 | CHEMBL3983300 | C29H33F6N3O2 | 569.592 | 9 / 1 | 6.2 | No |
538265 | CHEMBL3921582 | C30H38F3N3O2 | 529.648 | 6 / 1 | 6.1 | No |
538267 | CHEMBL3969571 | C28H33F6N3O3 | 573.58 | 10 / 2 | 4.7 | No |
538280 | CHEMBL3921675 | C25H27F3N2O3 | 460.497 | 6 / 1 | 4.7 | Yes |
538381 | CHEMBL3942644 | C22H21F6N3O2 | 473.419 | 9 / 2 | 3.8 | Yes |
538405 | CHEMBL3916690 | C28H33F6N3O2 | 557.581 | 9 / 1 | 6.0 | No |
538543 | CHEMBL3929013 | C26H24F6N2O4S | 574.538 | 10 / 1 | 3.7 | No |
538583 | SCHEMBL1603643 | C23H22F6N2O3 | 488.43 | 9 / 1 | 4.0 | Yes |
538674 | CHEMBL3946683 | C27H29F6N3O2 | 541.538 | 9 / 1 | 5.2 | No |
538720 | SCHEMBL1603530 | C22H20F6N2O2 | 458.404 | 8 / 1 | 4.9 | Yes |
538725 | CHEMBL3893852 | C25H22F6N2O2 | 496.453 | 8 / 1 | 5.3 | No |
538726 | CHEMBL3953664 | C25H22F6N2O2 | 496.453 | 8 / 1 | 5.3 | No |
538878 | SCHEMBL1603299 | C22H20F6N2O3 | 474.403 | 9 / 2 | 4.0 | Yes |
538924 | SCHEMBL1602444 | C26H26F6N2O3 | 528.495 | 9 / 1 | 4.7 | No |
538934 | CHEMBL3951255 | C20H16F6N2O2 | 430.35 | 8 / 1 | 4.0 | Yes |
538964 | CHEMBL3974566 | C21H21F3N2O3 | 406.405 | 6 / 1 | 3.4 | Yes |
539035 | CHEMBL3958290 | C19H18Cl2N2O2 | 377.265 | 2 / 1 | 3.8 | Yes |
539090 | CHEMBL3926348 | C31H35F6N3O4 | 627.628 | 10 / 1 | 5.8 | No |
539133 | CHEMBL3928096 | C25H26F6N2O3 | 516.484 | 9 / 1 | 4.8 | No |
539152 | CHEMBL3951472 | C24H24ClF3N2O2 | 464.913 | 5 / 1 | 5.4 | No |
539173 | CHEMBL3955807 | C27H31F6N3O2 | 543.554 | 9 / 1 | 5.5 | No |
539345 | CHEMBL3938817 | C20H18ClF3N2O2 | 410.821 | 5 / 1 | 4.1 | Yes |
539353 | CHEMBL3930907 | C25H26F6N2O2 | 500.485 | 8 / 1 | 6.1 | No |
539397 | CHEMBL3977233 | C26H28F6N2O2 | 514.512 | 8 / 1 | 6.4 | No |
539425 | CHEMBL3952934 | C24H24F6N2O3 | 502.457 | 9 / 2 | 4.2 | No |
539432 | CHEMBL3890766 | C25H24F6N2O2 | 498.469 | 8 / 1 | 5.9 | No |
539434 | CHEMBL3923540 | C28H34F3N3O2 | 501.594 | 6 / 1 | 5.1 | No |
539560 | CHEMBL3965837 | C21H24N2O2 | 336.435 | 2 / 1 | 3.4 | Yes |
539575 | CHEMBL3901740 | C26H27F6N3O2 | 527.511 | 9 / 1 | 4.7 | No |
539594 | CHEMBL3927309 | C23H24ClF3N2O2 | 452.902 | 5 / 1 | 5.4 | No |
539863 | CHEMBL3909448 | C24H27F3N2O3 | 448.486 | 6 / 1 | 4.7 | Yes |
539875 | CHEMBL3982032 | C24H27F3N2O2 | 432.487 | 5 / 1 | 5.1 | No |
549822 | CHEMBL3918834 | C28H33F6N3O2 | 557.581 | 9 / 1 | 6.1 | No |
539947 | CHEMBL3914663 | C23H24BrF3N2O2 | 497.356 | 5 / 1 | 5.3 | No |
539970 | CHEMBL3953770 | C24H27F3N2O2 | 432.487 | 5 / 1 | 5.1 | No |
540050 | CHEMBL3948212 | C23H21F7N2O2 | 490.422 | 9 / 1 | 5.2 | No |
540161 | CHEMBL3907211 | C22H20F6N2O3 | 474.403 | 9 / 1 | 4.3 | Yes |
540165 | CHEMBL3910762 | C29H34F5N3O2 | 551.602 | 8 / 1 | 5.8 | No |
540170 | CHEMBL3973464 | C24H24F6N2O3 | 502.457 | 9 / 2 | 4.2 | No |
540178 | CHEMBL3982735 | C30H38F3N3O3 | 545.647 | 7 / 1 | 5.6 | No |
540212 | CHEMBL3957545 | C23H20F6N2O3 | 486.414 | 9 / 1 | 4.3 | Yes |
540270 | CHEMBL3941195 | C25H27F6N3O2 | 515.5 | 9 / 1 | 4.8 | No |
540410 | CHEMBL3898515 | C29H32F7N3O2 | 587.583 | 10 / 1 | 5.8 | No |
540416 | CHEMBL3947900 | C26H28F6N2O2 | 514.512 | 8 / 1 | 6.4 | No |
540425 | CHEMBL3980302 | C22H23F3N2O2 | 404.433 | 5 / 1 | 4.2 | Yes |
540447 | CHEMBL3971243 | C27H29F6N3O3 | 557.537 | 10 / 1 | 4.4 | No |
540465 | CHEMBL3965949 | C26H26F9N3O2 | 583.499 | 12 / 1 | 5.9 | No |
540471 | CHEMBL3933817 | C24H24F6N2O2 | 486.458 | 8 / 1 | 5.6 | No |
540472 | CHEMBL3943742 | C24H24F6N2O2 | 486.458 | 8 / 1 | 5.6 | No |
540477 | CHEMBL3904343 | C29H33F6N3O2 | 569.592 | 9 / 1 | 5.9 | No |
540524 | CHEMBL3937288 | C21H21F3N2O2 | 390.406 | 5 / 1 | 3.9 | Yes |
540654 | CHEMBL3931112 | C27H27F6N3O2 | 539.522 | 9 / 1 | 4.4 | No |
540664 | CHEMBL3908495 | C28H34F5N3O2 | 539.591 | 8 / 1 | 5.8 | No |
540666 | CHEMBL3921777 | C27H29ClF5N3O2 | 557.99 | 8 / 1 | 5.7 | No |
540700 | CHEMBL3941761 | C26H29F6N3O2 | 529.527 | 9 / 1 | 5.1 | No |
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