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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3894891
Molecular formula	C29H33F6N3O2
IUPAC name	(3R,4S)-N-[3,5-bis(trifluoromethyl)phenyl]-3-[[cyclobutylmethyl(methyl)amino]methyl]-1-(2,6-dimethylphenyl)-4-methyl-5-oxopyrrolidine-3-carboxamide
Molecular weight	569.592
Hydrogen bond acceptor	9
Hydrogen bond donor	1
XlogP	6.0
Synonyms	SCHEMBL15251142
Inchi Key	AFHOBGBVUWVPTC-XHCCPWGMSA-N
Inchi ID	InChI=1S/C29H33F6N3O2/c1-17-7-5-8-18(2)24(17)38-16-27(19(3)25(38)39,15-37(4)14-20-9-6-10-20)26(40)36-23-12-21(28(30,31)32)11-22(13-23)29(33,34)35/h5,7-8,11-13,19-20H,6,9-10,14-16H2,1-4H3,(H,36,40)/t19-,27-/m1/s1
PubChem CID	89799789
ChEMBL	CHEMBL3894891
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
536036	Chemokine-like receptor 1	Q99788	CMKLR1	Homo sapiens (Human)	373

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