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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SCHEMBL1604237
Molecular formula	C24H24F3N3O2
IUPAC name	(3R)-N-[3-cyano-5-(trifluoromethyl)phenyl]-1-(2,6-dimethylphenyl)-5-oxo-3-propan-2-ylpyrrolidine-3-carboxamide
Molecular weight	443.47
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	4.3
Synonyms	CHEMBL3981730 (R)-N-(3-cyano-5-(trifluoromethyl)phenyl)-1-(2,6-dimethylphenyl)-3-isopropyl-5-oxopyrrolidine-3-carboxamide CQIOBGAMEQMMPD-QHCPKHFHSA-N
Inchi Key	CQIOBGAMEQMMPD-QHCPKHFHSA-N
Inchi ID	InChI=1S/C24H24F3N3O2/c1-14(2)23(11-20(31)30(13-23)21-15(3)6-5-7-16(21)4)22(32)29-19-9-17(12-28)8-18(10-19)24(25,26)27/h5-10,14H,11,13H2,1-4H3,(H,29,32)/t23-/m0/s1
PubChem CID	51034451
ChEMBL	CHEMBL3981730
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
537202	Chemokine-like receptor 1	Q99788	CMKLR1	Homo sapiens (Human)	373

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