You can:
Name | Chemokine-like receptor 1 |
---|---|
Species | Homo sapiens (Human) |
Gene | CMKLR1 |
Synonym | tazarotene induced gene 2 receptor RVER1 resolvin E1 receptor Gpcr27 G-protein coupled receptor DEZ [ Show all ] |
Disease | N/A |
Length | 373 |
Amino acid sequence | MRMEDEDYNTSISYGDEYPDYLDSIVVLEDLSPLEARVTRIFLVVVYSIVCFLGILGNGLVIIIATFKMKKTVNMVWFLNLAVADFLFNVFLPIHITYAAMDYHWVFGTAMCKISNFLLIHNMFTSVFLLTIISSDRCISVLLPVWSQNHRSVRLAYMACMVIWVLAFFLSSPSLVFRDTANLHGKISCFNNFSLSTPGSSSWPTHSQMDPVGYSRHMVVTVTRFLCGFLVPVLIITACYLTIVCKLQRNRLAKTKKPFKIIVTIIITFFLCWCPYHTLNLLELHHTAMPGSVFSLGLPLATALAIANSCMNPILYVFMGQDFKKFKVALFSRLVNALSEDTGHSSYPSHRSFTKMSSMNERTSMNERETGML |
UniProt | Q99788 |
Protein Data Bank | N/A |
GPCR-HGmod model | Q99788 |
3D structure model | This predicted structure model is from GPCR-EXP Q99788. |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL3540 |
IUPHAR | 79 |
DrugBank | N/A |
Name | CHEMBL3951255 |
---|---|
Molecular formula | C20H16F6N2O2 |
IUPAC name | N-[3,5-bis(trifluoromethyl)phenyl]-1-(2-methylphenyl)-5-oxopyrrolidine-3-carboxamide |
Molecular weight | 430.35 |
Hydrogen bond acceptor | 8 |
Hydrogen bond donor | 1 |
XlogP | 4.0 |
Synonyms | SCHEMBL12728546 |
Inchi Key | HNFFDQALNHAYGR-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C20H16F6N2O2/c1-11-4-2-3-5-16(11)28-10-12(6-17(28)29)18(30)27-15-8-13(19(21,22)23)7-14(9-15)20(24,25)26/h2-5,7-9,12H,6,10H2,1H3,(H,27,30) |
PubChem CID | 88954742 |
ChEMBL | CHEMBL3951255 |
IUPHAR | N/A |
BindingDB | N/A |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand satisfies Lipinski's rule of five. |
Parameter | Value | Reference | Database source |
---|---|---|---|
IC50 | >30.0 nM | None | ChEMBL |
zhanglabzhanggroup.org | +65-6601-1241 | Computing 1, 13 Computing Drive, Singapore 117417