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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Chemokine-like receptor 1
Species	Homo sapiens (Human)
Gene	CMKLR1
Synonym	tazarotene induced gene 2 receptor RVER1 resolvin E1 receptor Gpcr27 G-protein coupled receptor DEZ G-protein coupled receptor ChemR23 CMKLR1 chemokine receptor-like 1 Chemerin1 chemerin receptor 1 TIG2 receptor [ Show all ]
Disease	N/A
Length	373
Amino acid sequence	MRMEDEDYNTSISYGDEYPDYLDSIVVLEDLSPLEARVTRIFLVVVYSIVCFLGILGNGLVIIIATFKMKKTVNMVWFLNLAVADFLFNVFLPIHITYAAMDYHWVFGTAMCKISNFLLIHNMFTSVFLLTIISSDRCISVLLPVWSQNHRSVRLAYMACMVIWVLAFFLSSPSLVFRDTANLHGKISCFNNFSLSTPGSSSWPTHSQMDPVGYSRHMVVTVTRFLCGFLVPVLIITACYLTIVCKLQRNRLAKTKKPFKIIVTIIITFFLCWCPYHTLNLLELHHTAMPGSVFSLGLPLATALAIANSCMNPILYVFMGQDFKKFKVALFSRLVNALSEDTGHSSYPSHRSFTKMSSMNERTSMNERETGML
UniProt	Q99788
Protein Data Bank	N/A
GPCR-HGmod model	Q99788
3D structure model	This predicted structure model is from GPCR-EXP Q99788.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3540
IUPHAR	79
DrugBank	N/A

Ligand

Name	CHEMBL3909448
Molecular formula	C24H27F3N2O3
IUPAC name	(3S,4S)-1-(2,6-dimethylphenyl)-3-ethyl-N-[3-methoxy-5-(trifluoromethyl)phenyl]-4-methyl-5-oxopyrrolidine-3-carboxamide
Molecular weight	448.486
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	4.7
Synonyms	SCHEMBL15251175
Inchi Key	JHSNMJINMARKTQ-WAIKUNEKSA-N
Inchi ID	InChI=1S/C24H27F3N2O3/c1-6-23(13-29(21(30)16(23)4)20-14(2)8-7-9-15(20)3)22(31)28-18-10-17(24(25,26)27)11-19(12-18)32-5/h7-12,16H,6,13H2,1-5H3,(H,28,31)/t16-,23-/m1/s1
PubChem CID	51034006
ChEMBL	CHEMBL3909448
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	>30.0 nM	None	ChEMBL

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