You can:
| Name | C-C chemokine receptor type 4 |
|---|---|
| Species | Mus musculus (Mouse) |
| Gene | Ccr4 |
| Synonym | chemokine (C-C motif) receptor 4 CD194 CCR4 CCR-4 CC-CKR-4 [ Show all ] |
| Disease | N/A for non-human GPCRs |
| Length | 360 |
| Amino acid sequence | MNATEVTDTTQDETVYNSYYFYESMPKPCTKEGIKAFGEVFLPPLYSLVFLLGLFGNSVVVLVLFKYKRLKSMTDVYLLNLAISDLLFVLSLPFWGYYAADQWVFGLGLCKIVSWMYLVGFYSGIFFIMLMSIDRYLAIVHAVFSLKARTLTYGVITSLITWSVAVFASLPGLLFSTCYTEHNHTYCKTQYSVNSTTWKVLSSLEINVLGLLIPLGIMLFCYSMIIRTLQHCKNEKKNRAVRMIFAVVVLFLGFWTPYNVVLFLETLVELEVLQDCTLERYLDYAIQATETLAFIHCCLNPVIYFFLGEKFRKYITQLFRTCRGPLVLCKHCDFLQVYSADMSSSSYTQSTVDHDFRDAL |
| UniProt | P51680 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL5410 |
| IUPHAR | 61 |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 1132 |  CHEMBL488690 | C27H37ClN6O2 | 513.083 | 8 / 1 | 5.4 | No |
| 15111 |  CHEMBL496151 | C26H32ClN5O3 | 498.024 | 8 / 2 | 4.9 | Yes |
| 23934 |  CHEMBL453594 | C27H40FN5O2 | 485.648 | 8 / 1 | 6.1 | No |
| 45349 |  CHEMBL487835 | C25H30FN5O2 | 451.546 | 8 / 1 | 5.0 | Yes |
| 46560 |  CHEMBL488857 | C25H32ClN5O3 | 486.013 | 8 / 2 | 4.7 | Yes |
| 59377 |  CHEMBL451783 | C28H43N5O2 | 481.685 | 7 / 1 | 6.5 | No |
| 72994 |  CHEMBL459464 | C25H37N5O | 423.605 | 6 / 1 | 5.7 | No |
| 553672 |  AZD2098 | C11H9Cl2N3O3S | 334.171 | 6 / 1 | 2.6 | Yes |
| 86286 |  CHEMBL516936 | C25H37N5O | 423.605 | 6 / 1 | 5.7 | No |
| 87525 |  CHEMBL486656 | C26H34ClN5O3 | 500.04 | 8 / 2 | 5.1 | No |
| 93890 |  CHEMBL233046 | C24H27Cl2N7O | 500.428 | 7 / 2 | 4.1 | No |
| 114697 |  CHEMBL486840 | C25H30ClN5O2 | 467.998 | 7 / 1 | 5.5 | No |
| 116682 |  CHEMBL488704 | C25H30BrN5O2 | 512.452 | 7 / 1 | 5.6 | No |
| 127535 |  C-014C | C22H32N4O2 | 384.524 | 6 / 2 | 5.7 | No |
| 140910 |  CHEMBL459463 | C27H41N5O2 | 467.658 | 7 / 1 | 6.2 | No |
| 142093 |  CHEMBL526474 | C28H36ClN5O3 | 526.078 | 8 / 1 | 5.6 | No |
| 151426 |  CHEMBL496787 | C26H32ClN5O4 | 514.023 | 9 / 2 | 4.0 | No |
| 160484 |  CHEMBL495736 | C28H36ClN5O3 | 526.078 | 8 / 2 | 5.0 | No |
| 209427 |  CHEMBL496356 | C27H34ClN5O3 | 512.051 | 8 / 2 | 5.1 | No |
| 554425 |  AZD-1678 | C11H8Cl2FN3O3S | 352.161 | 7 / 1 | 2.6 | Yes |
| 268167 |  CHEMBL495737 | C29H38ClN5O3 | 540.105 | 8 / 2 | 5.5 | No |
| 311618 |  CHEMBL488018 | C25H29F2N5O2 | 469.537 | 9 / 1 | 5.1 | No |
| 361985 |  CHEMBL521737 | C28H43N5O3 | 497.684 | 8 / 2 | 5.3 | No |
| 378463 |  CHEMBL496152 | C27H34ClN5O3 | 512.051 | 8 / 1 | 5.4 | No |
| 385725 |  CCR4 Antagonist | C27H41N5O2 | 467.658 | 7 / 1 | 6.0 | No |
| 405833 |  CHEMBL487635 | C26H39N5O2 | 453.631 | 7 / 1 | 5.7 | No |
zhanglab
zhanggroup.org | +65-6601-1241 | Computing 1, 13 Computing Drive, Singapore 117417