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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL488018
Molecular formula	C25H29F2N5O2
IUPAC name	N-(3,4-difluorophenyl)-6,7-dimethoxy-2-(4-pyrrolidin-1-ylpiperidin-1-yl)quinazolin-4-amine
Molecular weight	469.537
Hydrogen bond acceptor	9
Hydrogen bond donor	1
XlogP	5.1
Synonyms	N-(3,4-Difluorophenyl)-6,7-dimethoxy-2-(4-pyrrolidin-1-ylpiperidin-1-yl)quinazolin-4-amine BDBM50245034
Inchi Key	SDLZTFYVGPVSQZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H29F2N5O2/c1-33-22-14-18-21(15-23(22)34-2)29-25(30-24(18)28-16-5-6-19(26)20(27)13-16)32-11-7-17(8-12-32)31-9-3-4-10-31/h5-6,13-15,17H,3-4,7-12H2,1-2H3,(H,28,29,30)
PubChem CID	44562155
ChEMBL	CHEMBL488018
IUPHAR	N/A
BindingDB	50245034
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
311617	C-C chemokine receptor type 4	P51679	CCR4	Homo sapiens (Human)	360
311618	C-C chemokine receptor type 4	P51680	Ccr4	Mus musculus (Mouse)	360

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