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| Name | C-C chemokine receptor type 4 |
|---|---|
| Species | Homo sapiens (Human) |
| Gene | CCR4 |
| Synonym | K5-5 ChemR13 chemokine (C-C motif) receptor 4 CD194 CCR4 [ Show all ] |
| Disease | Asthma Atopic dermatitis Autoimmune diabetes |
| Length | 360 |
| Amino acid sequence | MNPTDIADTTLDESIYSNYYLYESIPKPCTKEGIKAFGELFLPPLYSLVFVFGLLGNSVVVLVLFKYKRLRSMTDVYLLNLAISDLLFVFSLPFWGYYAADQWVFGLGLCKMISWMYLVGFYSGIFFVMLMSIDRYLAIVHAVFSLRARTLTYGVITSLATWSVAVFASLPGFLFSTCYTERNHTYCKTKYSLNSTTWKVLSSLEINILGLVIPLGIMLFCYSMIIRTLQHCKNEKKNKAVKMIFAVVVLFLGFWTPYNIVLFLETLVELEVLQDCTFERYLDYAIQATETLAFVHCCLNPIIYFFLGEKFRKYILQLFKTCRGLFVLCQYCGLLQIYSADTPSSSYTQSTMDHDLHDAL |
| UniProt | P51679 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | P51679 |
| 3D structure model | This predicted structure model is from GPCR-EXP P51679. |
| BioLiP | N/A |
| Therapeutic Target Database | T06955 |
| ChEMBL | CHEMBL2414 |
| IUPHAR | 61 |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 485 |  CHEMBL195203 | C25H32N4 | 388.559 | 4 / 1 | 6.1 | No |
| 1125 |  CHEMBL382826 | C22H27Cl2N5O2 | 464.391 | 6 / 0 | 3.5 | Yes |
| 1131 |  CHEMBL488690 | C27H37ClN6O2 | 513.083 | 8 / 1 | 5.4 | No |
| 3080 |  CHEMBL206039 | C16H17N3S | 283.393 | 4 / 1 | 4.8 | Yes |
| 4909 |  CHEMBL2207082 | C15H11Cl3N4O2S | 417.689 | 5 / 1 | 3.4 | Yes |
| 5620 |  3-chloro-5,7-dihydroxy-4-methyl-2H-chromen-2-one | C10H7ClO4 | 226.612 | 4 / 2 | 2.0 | Yes |
| 5938 |  CHEMBL603701 | C23H22N2O5 | 406.438 | 6 / 2 | 2.8 | Yes |
| 10659 |  CHEMBL246584 | C24H33N3O3S | 443.606 | 5 / 1 | 4.1 | Yes |
| 14289 |  CHEMBL296152 | C28H30Cl2F4N4O4S | 665.526 | 10 / 2 | 4.2 | No |
| 14673 |  SCHEMBL358030 | C22H21ClN4O4S2 | 505.004 | 7 / 3 | 3.2 | No |
| 15102 |  disulfiram | C10H20N2S4 | 296.524 | 4 / 0 | 3.9 | Yes |
| 15110 |  CHEMBL496151 | C26H32ClN5O3 | 498.024 | 8 / 2 | 4.9 | Yes |
| 18157 |  CHEMBL198077 | C21H27Cl2N5O2 | 452.38 | 6 / 2 | 4.3 | Yes |
| 18471 |  CHEMBL602887 | C17H22N2O3 | 302.374 | 5 / 0 | 2.3 | Yes |
| 21179 |  CHEMBL508170 | C26H34N4O2 | 434.584 | 6 / 1 | 6.6 | No |
| 21334 |  CHEMBL510584 | C27H35N5O2 | 461.61 | 7 / 1 | 6.2 | No |
| 21829 |  CHEMBL415902 | C33H36Cl2N4O4S | 655.635 | 6 / 2 | 4.8 | No |
| 22341 |  CHEMBL43092 | C31H34Cl2N4O4S | 629.597 | 6 / 2 | 4.5 | No |
| 22502 |  BDBM81855 | C30H48N6O4 | 556.752 | 7 / 1 | 2.6 | No |
| 23933 |  CHEMBL453594 | C27H40FN5O2 | 485.648 | 8 / 1 | 6.1 | No |
| 24196 |  CHEMBL42226 | C27H31Cl3N4O4S | 613.979 | 6 / 2 | 3.8 | No |
| 25044 |  CHEMBL512692 | C21H31N5O2 | 385.512 | 7 / 1 | 3.7 | Yes |
| 26110 |  CHEMBL290845 | C28H30Cl2N4O3S | 573.533 | 5 / 2 | 4.5 | No |
| 26242 |  CHEMBL2326622 | C26H28ClN5O4S2 | 574.111 | 8 / 3 | 4.6 | No |
| 26711 |  CHEMBL496147 | C28H34ClN5O4 | 540.061 | 8 / 2 | 4.4 | No |
| 26742 |  CHEMBL2018963 | C22H21ClN4O4S2 | 505.004 | 7 / 1 | 4.4 | No |
| 30598 |  AC1LA88L | C37H43N5O4 | 621.782 | 5 / 2 | 5.7 | No |
| 30812 |  CHEMBL245313 | C29H34FN3O3S | 523.667 | 6 / 0 | 5.0 | No |
| 536795 |  CHEMBL3889627 | C23H27N5O3S | 453.561 | 5 / 2 | 2.6 | Yes |
| 31063 |  CHEMBL2326623 | C25H26ClN5O5S2 | 576.083 | 9 / 3 | 3.3 | No |
| 31064 |  CHEMBL2326624 | C25H26ClN5O5S2 | 576.083 | 9 / 3 | 3.3 | No |
| 32675 |  SCHEMBL357053 | C24H24ClFN4O5S2 | 567.047 | 9 / 3 | 4.1 | No |
| 33929 |  CHEMBL2018967 | C22H21ClN4O5S2 | 521.003 | 8 / 3 | 3.4 | No |
| 35024 |  CHEMBL600018 | C21H29N3O3 | 371.481 | 6 / 0 | 2.5 | Yes |
| 36448 |  CHEMBL105659 | C34H40N4O2 | 536.72 | 4 / 0 | 6.7 | No |
| 36528 |  CHEMBL2434978 | C32H36N4O4S | 572.724 | 7 / 1 | 2.1 | No |
| 37961 |  CHEMBL416069 | C31H42N4O4S | 566.761 | 6 / 2 | 4.1 | No |
| 38015 |  CHEMBL3138345 | C61H72Cl2O10 | 1036.14 | 10 / 4 | 18.1 | No |
| 38775 |  CHEMBL2113072 | C21H30ClN3O | 375.941 | 4 / 1 | 4.9 | Yes |
| 39268 |  CHEMBL2207101 | C16H11Cl2F3N4O2S | 451.245 | 8 / 1 | 3.9 | Yes |
| 41584 |  BDBM81845 | C29H40N6O2 | 504.679 | 5 / 1 | 3.3 | No |
| 443337 |  CHEMBL3310835 | C18H20Cl2N4O4S | 459.342 | 6 / 2 | 2.5 | Yes |
| 44036 |  CHEMBL207780 | C29H34F3N3 | 481.607 | 6 / 1 | 8.1 | No |
| 45350 |  CHEMBL487835 | C25H30FN5O2 | 451.546 | 8 / 1 | 5.0 | Yes |
| 522848 |  CHEMBL3799865 | C24H30F2N6O | 456.542 | 8 / 2 | 3.0 | Yes |
| 46561 |  CHEMBL488857 | C25H32ClN5O3 | 486.013 | 8 / 2 | 4.7 | Yes |
| 558715 |  SCHEMBL356927 | C21H19ClN4O4S2 | 490.977 | 7 / 3 | 4.3 | Yes |
| 47013 |  CHEMBL2216810 | C33H38Cl2N4O3S | 641.652 | 5 / 2 | 6.1 | No |
| 47014 |  CHEMBL42334 | C33H38Cl2N4O3S | 641.652 | 5 / 2 | 6.1 | No |
| 47454 |  CHEMBL195698 | C23H30N4 | 362.521 | 4 / 1 | 5.7 | No |
| 47973 |  CHEMBL2207086 | C15H13ClN4O2S | 348.805 | 5 / 1 | 2.4 | Yes |
| 51259 |  CHEMBL394714 | C28H33N3O3S | 491.65 | 5 / 0 | 4.5 | Yes |
| 51303 |  CHEMBL602268 | C21H22N2O5 | 382.416 | 7 / 2 | 3.0 | Yes |
| 51606 |  CHEMBL297335 | C29H31Cl2N3O3S | 572.545 | 5 / 1 | 5.1 | No |
| 51744 |  CHEMBL439518 | C18H21N3S | 311.447 | 4 / 1 | 4.7 | Yes |
| 51794 |  CHEMBL600019 | C14H16N2O4 | 276.292 | 6 / 3 | 0.8 | Yes |
| 53053 |  1269775-42-9 | C24H34ClN7O3 | 504.032 | 7 / 3 | N/A | No |
| 53237 |  PharmaGSID_48521 | C31H49N5O4 | 555.764 | 7 / 0 | 4.1 | No |
| 443835 |  CHEMBL3310833 | C17H15Cl2N3O5S | 444.283 | 6 / 2 | 2.2 | Yes |
| 54465 |  CHEMBL205195 | C14H13N3S | 255.339 | 4 / 2 | 3.0 | Yes |
| 523130 |  CHEMBL3798941 | C26H31Cl2F3N6O3 | 603.468 | 11 / 3 | N/A | No |
| 55090 |  CHEMBL42044 | C33H36Cl2N4O4S | 655.635 | 6 / 2 | 4.8 | No |
| 55143 |  5,7-Dihydroxy-4-trifluoromethylcoumarin | C10H5F3O4 | 246.141 | 7 / 2 | 1.6 | Yes |
| 55390 |  AC1LAJEP | C39H44ClN5O4 | 682.262 | 5 / 2 | 7.2 | No |
| 55504 |  CHEMBL601424 | C21H20N2O5 | 380.4 | 6 / 2 | 2.4 | Yes |
| 56004 |  CHEMBL2326628 | C21H20ClN5O4S2 | 505.992 | 8 / 2 | 3.0 | No |
| 56927 |  BDBM81829 | C31H43N5O3 | 533.717 | 5 / 1 | 3.9 | No |
| 59376 |  CHEMBL451783 | C28H43N5O2 | 481.685 | 7 / 1 | 6.5 | No |
| 62809 |  BDBM81844 | C28H38N6O2 | 490.652 | 5 / 1 | 2.9 | Yes |
| 62908 |  CHEMBL2018957 | C20H18ClN3O4S2 | 463.951 | 7 / 1 | 4.9 | Yes |
| 63337 |  CHEMBL2207085 | C15H12Cl3N5O2S | 432.704 | 6 / 1 | 3.9 | Yes |
| 63369 |  CHEMBL470960 | C27H35N5O2 | 461.61 | 7 / 1 | 5.3 | No |
| 63875 |  CHEMBL245331 | C29H33Cl2N3O3S | 574.561 | 5 / 0 | 6.2 | No |
| 64541 |  CHEMBL206789 | C15H20N2S | 260.399 | 3 / 1 | 5.3 | No |
| 64791 |  CHEMBL246986 | C29H35N3O3S | 505.677 | 5 / 0 | 4.9 | No |
| 66114 |  CHEMBL297854 | C27H29Cl2N3O2S | 530.508 | 4 / 1 | 5.5 | No |
| 66977 |  CHEMBL2207100 | C13H9Cl3N4O2S2 | 423.711 | 6 / 1 | 4.0 | Yes |
| 444391 |  CHEMBL3310838 | C19H18Cl2N4O5S | 485.336 | 6 / 2 | 1.8 | Yes |
| 523552 |  CHEMBL3797946 | C26H30Cl2F6N6O5 | 691.453 | 16 / 4 | N/A | No |
| 69625 |  CHEMBL275593 | C33H38Cl2N4O4S | 657.651 | 6 / 2 | 5.2 | No |
| 69745 |  CHEMBL2207088 | C15H12Cl2N4O2S | 383.247 | 5 / 1 | 3.1 | Yes |
| 70450 |  CHEMBL43758 | C31H34Cl2N4O4S | 629.597 | 6 / 2 | 4.5 | No |
| 72993 |  CHEMBL459464 | C25H37N5O | 423.605 | 6 / 1 | 5.7 | No |
| 74302 |  CHEMBL195484 | C18H24Cl2N4O | 383.317 | 5 / 1 | 4.7 | Yes |
| 523733 |  CHEMBL3799904 | C24H30Cl2N6O | 489.445 | 6 / 2 | 4.1 | Yes |
| 523734 |  CHEMBL3799025 | C24H30Cl2N6O | 489.445 | 6 / 2 | 4.1 | Yes |
| 523735 |  CHEMBL3798263 | C24H30Cl2N6O | 489.445 | 6 / 2 | 4.1 | Yes |
| 523762 |  CHEMBL3797678 | C19H25Cl4N5 | 465.244 | 5 / 4 | N/A | N/A |
| 76131 |  CHEMBL207801 | C15H14N2S | 254.351 | 3 / 0 | 4.6 | Yes |
| 77328 |  CHEMBL44134 | C26H38Cl2N4O4S | 573.574 | 6 / 2 | 3.8 | No |
| 77875 |  CHEMBL471735 | C24H35N5O2 | 425.577 | 7 / 0 | 4.3 | Yes |
| 444757 |  CHEMBL3310825 | C15H13Cl2N3O3S | 386.247 | 5 / 1 | 3.7 | Yes |
| 78099 |  CHEMBL377421 | C29H30F3N3S | 509.635 | 7 / 1 | 8.7 | No |
| 78975 |  CHEMBL195103 | C20H28Cl2N4O | 411.371 | 5 / 1 | 5.5 | No |
| 79556 |  CHEMBL2435856 | C34H40N4O5 | 584.717 | 7 / 1 | 2.4 | No |
| 81119 |  CHEMBL394467 | C26H30N4O3S | 478.611 | 6 / 1 | 3.2 | Yes |
| 553671 |  AZD2098 | C11H9Cl2N3O3S | 334.171 | 6 / 1 | 2.6 | Yes |
| 81570 |  BDBM81833 | C26H42N6O2 | 470.662 | 5 / 1 | 2.3 | Yes |
| 83083 |  UNII-HD099HOT7H | C30H37Cl2IN2O2 | 655.442 | 3 / 1 | N/A | No |
| 83190 |  CHEMBL601653 | C16H20N2O4 | 304.346 | 6 / 1 | 1.6 | Yes |
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