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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL451783
Molecular formula	C28H43N5O2
IUPAC name	N-cycloheptyl-2-[4-[cyclopentyl(methyl)amino]piperidin-1-yl]-6,7-dimethoxyquinazolin-4-amine
Molecular weight	481.685
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	6.5
Synonyms	BDBM50244083 N-cycloheptyl-2-(4-(cyclopentyl(methyl)amino)piperidin-1-yl)-6,7-dimethoxyquinazolin-4-amine
Inchi Key	DGLJOEVJJUYDCB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H43N5O2/c1-32(21-12-8-9-13-21)22-14-16-33(17-15-22)28-30-24-19-26(35-3)25(34-2)18-23(24)27(31-28)29-20-10-6-4-5-7-11-20/h18-22H,4-17H2,1-3H3,(H,29,30,31)
PubChem CID	44561294
ChEMBL	CHEMBL451783
IUPHAR	N/A
BindingDB	50244083
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
59376	C-C chemokine receptor type 4	P51679	CCR4	Homo sapiens (Human)	360
59377	C-C chemokine receptor type 4	P51680	Ccr4	Mus musculus (Mouse)	360

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