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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL488690
Molecular formula	C27H37ClN6O2
IUPAC name	N-(4-chlorophenyl)-2-[4-[2-(diethylamino)ethyl]-1,4-diazepan-1-yl]-6,7-dimethoxyquinazolin-4-amine
Molecular weight	513.083
Hydrogen bond acceptor	8
Hydrogen bond donor	1
XlogP	5.4
Synonyms	BDBM50245112 N-(4-Chlorophenyl)-2-{4-[2-(diethylamino)ethyl]-1,4-diazepan-1-yl}-6,7-dimethoxyquinazolin-4-amine
Inchi Key	ABSJDAAPHZEZFF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H37ClN6O2/c1-5-32(6-2)14-15-33-12-7-13-34(17-16-33)27-30-23-19-25(36-4)24(35-3)18-22(23)26(31-27)29-21-10-8-20(28)9-11-21/h8-11,18-19H,5-7,12-17H2,1-4H3,(H,29,30,31)
PubChem CID	44562236
ChEMBL	CHEMBL488690
IUPHAR	N/A
BindingDB	50245112
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
1131	C-C chemokine receptor type 4	P51679	CCR4	Homo sapiens (Human)	360
1132	C-C chemokine receptor type 4	P51680	Ccr4	Mus musculus (Mouse)	360

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