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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	C-014C
Molecular formula	C22H32N4O2
IUPAC name	4-N-cycloheptyl-2-N-cyclopentyl-6,7-dimethoxyquinazoline-2,4-diamine
Molecular weight	384.524
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	5.7
Synonyms	N-Cycloheptyl-2-[4-(cyclopentylamino)piperidine-1-yl]-6,7-dimethoxyquinazolin-4-amine BDBM50244050 CHEMBL509396 D0EV1I
Inchi Key	HZBKRPBMAVNOCZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H32N4O2/c1-27-19-13-17-18(14-20(19)28-2)25-22(24-16-11-7-8-12-16)26-21(17)23-15-9-5-3-4-6-10-15/h13-16H,3-12H2,1-2H3,(H2,23,24,25,26)
PubChem CID	44561260
ChEMBL	CHEMBL509396
IUPHAR	N/A
BindingDB	50244050
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
127534	C-C chemokine receptor type 4	P51679	CCR4	Homo sapiens (Human)	360
127535	C-C chemokine receptor type 4	P51680	Ccr4	Mus musculus (Mouse)	360

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