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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL488704
Molecular formula	C25H30BrN5O2
IUPAC name	N-(3-bromophenyl)-6,7-dimethoxy-2-(4-pyrrolidin-1-ylpiperidin-1-yl)quinazolin-4-amine
Molecular weight	512.452
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	5.6
Synonyms	BDBM50245035 N-(3-Bromophenyl)-6,7-dimethoxy-2-(4-pyrrolidin-1-ylpiperidin-1-yl)quinazolin-4-amine
Inchi Key	HJQMVMHBYLQUMC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H30BrN5O2/c1-32-22-15-20-21(16-23(22)33-2)28-25(29-24(20)27-18-7-5-6-17(26)14-18)31-12-8-19(9-13-31)30-10-3-4-11-30/h5-7,14-16,19H,3-4,8-13H2,1-2H3,(H,27,28,29)
PubChem CID	44562156
ChEMBL	CHEMBL488704
IUPHAR	N/A
BindingDB	50245035
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
116681	C-C chemokine receptor type 4	P51679	CCR4	Homo sapiens (Human)	360
116682	C-C chemokine receptor type 4	P51680	Ccr4	Mus musculus (Mouse)	360

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