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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	C-C chemokine receptor type 4
Species	Mus musculus (Mouse)
Gene	Ccr4
Synonym	chemokine (C-C motif) receptor 4 CD194 CCR4 CCR-4 CC-CKR-4 CC CKR4 C-C CKR-4 C-C chemokine receptor 4 ChemR13 [ Show all ]
Disease	N/A for non-human GPCRs
Length	360
Amino acid sequence	MNATEVTDTTQDETVYNSYYFYESMPKPCTKEGIKAFGEVFLPPLYSLVFLLGLFGNSVVVLVLFKYKRLKSMTDVYLLNLAISDLLFVLSLPFWGYYAADQWVFGLGLCKIVSWMYLVGFYSGIFFIMLMSIDRYLAIVHAVFSLKARTLTYGVITSLITWSVAVFASLPGLLFSTCYTEHNHTYCKTQYSVNSTTWKVLSSLEINVLGLLIPLGIMLFCYSMIIRTLQHCKNEKKNRAVRMIFAVVVLFLGFWTPYNVVLFLETLVELEVLQDCTLERYLDYAIQATETLAFIHCCLNPVIYFFLGEKFRKYITQLFRTCRGPLVLCKHCDFLQVYSADMSSSSYTQSTVDHDFRDAL
UniProt	P51680
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5410
IUPHAR	61
DrugBank	N/A

Ligand

Name	CHEMBL488704
Molecular formula	C25H30BrN5O2
IUPAC name	N-(3-bromophenyl)-6,7-dimethoxy-2-(4-pyrrolidin-1-ylpiperidin-1-yl)quinazolin-4-amine
Molecular weight	512.452
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	5.6
Synonyms	N-(3-Bromophenyl)-6,7-dimethoxy-2-(4-pyrrolidin-1-ylpiperidin-1-yl)quinazolin-4-amine BDBM50245035
Inchi Key	HJQMVMHBYLQUMC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H30BrN5O2/c1-32-22-15-20-21(16-23(22)33-2)28-25(29-24(20)27-18-7-5-6-17(26)14-18)31-12-8-19(9-13-31)30-10-3-4-11-30/h5-7,14-16,19H,3-4,8-13H2,1-2H3,(H,27,28,29)
PubChem CID	44562156
ChEMBL	CHEMBL488704
IUPHAR	N/A
BindingDB	50245035
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Inhibition	11.0 %	PMID18694645	ChEMBL

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