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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL521737
Molecular formula	C28H43N5O3
IUPAC name	[1-[1-[4-(cycloheptylamino)-6,7-dimethoxyquinazolin-2-yl]piperidin-4-yl]piperidin-3-yl]methanol
Molecular weight	497.684
Hydrogen bond acceptor	8
Hydrogen bond donor	2
XlogP	5.3
Synonyms	{1''-[4-(Cycloheptylamino)-6,7-dimethoxyquinazolin-2-yl]-1,4''-bipiperidin-3-yl}methanol BDBM50265742
Inchi Key	VQVJOORGRHBCAX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H43N5O3/c1-35-25-16-23-24(17-26(25)36-2)30-28(31-27(23)29-21-9-5-3-4-6-10-21)32-14-11-22(12-15-32)33-13-7-8-20(18-33)19-34/h16-17,20-22,34H,3-15,18-19H2,1-2H3,(H,29,30,31)
PubChem CID	25212472
ChEMBL	CHEMBL521737
IUPHAR	N/A
BindingDB	50265742
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
361985	C-C chemokine receptor type 4	P51680	Ccr4	Mus musculus (Mouse)	360
361986	C-C chemokine receptor type 4	P51679	CCR4	Homo sapiens (Human)	360

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